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Knowledge regarding disease metabolism is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The review examines the cell metabolism of glucose, nucleotides, and lipids during homeostatic and pathological conditions of neurotoxicity, neuroimmunological disease, Parkinson\u2019s disease, thymoma in myasthenia gravis, and colorectal cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data collection includes electronic databases, the National Center for Biotechnology Information, and Google Scholar, with several inclusion criteria: cell metabolism, glucose metabolism, nucleotide metabolism, and lipid metabolism in health and disease patients suffering from neurotoxicity, neuroinflammation, Parkinson\u2019s disease, thymoma in myasthenia gravis. The initial number of collected and analyzed papers is 250. The final analysis included 150 studies out of 94 selected papers. After the selection process, 62.67% remains useful.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results and Conclusion<\/jats:title>\n                    <jats:p>A literature search shows that signaling molecules are involved in metabolic changes in cells. Differences between cancer and neuroimmunological diseases are present in the result section. Our finding enables insight into novel therapeutic targets and the development of scientific approaches for cancer and neurological disease onset, outcome, progression, and treatment, highlighting the importance of metabolic dysregulation. Current understanding, emerging research technologies and potential therapeutic interventions in metabolic programming is disucussed and highlighted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03946320241250293","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T07:04:13Z","timestamp":1715065453000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Uncovering novel therapeutic targets in glucose, nucleotides and lipids metabolism during cancer and neurological diseases"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6087-0620","authenticated-orcid":false,"given":"Sne\u017eana M","family":"Jovi\u010di\u0107","sequence":"first","affiliation":[{"name":"Department of Genetics, Faculty of Biology, University of Belgrade, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,5,7]]},"reference":[{"key":"bibr1-03946320241250293","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-022-00524-0"},{"key":"bibr2-03946320241250293","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.15376"},{"key":"bibr3-03946320241250293","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2019.21.2\/nsurana"},{"key":"bibr4-03946320241250293","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.705920"},{"key":"bibr5-03946320241250293","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9999146"},{"key":"bibr6-03946320241250293","doi-asserted-by":"publisher","DOI":"10.3390\/biom10101437"},{"key":"bibr7-03946320241250293","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.15169"},{"key":"bibr8-03946320241250293","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-021-10006-2"},{"key":"bibr9-03946320241250293","unstructured":"World Cancer Research Fund International. 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