{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:49:28Z","timestamp":1777520968743,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2002,9,1]],"date-time":"2002-09-01T00:00:00Z","timestamp":1030838400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can J Psychiatry"],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To examine the efficacy of atypical neuroleptics for decreasing craving and drug relapses during protracted withdrawal in individuals dually diagnosed with schizophrenia and cocaine dependence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>We conducted a 6-week, open-label pilot study comparing risperidone with typical neuroleptics in a sample of withdrawn cocaine-dependent schizophrenia patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Preliminary results suggest that individuals treated with risperidone had significantly less cue-elicited craving and substance abuse relapses at study completion. Further, they showed a trend toward a greater reduction in negative and global symptoms of schizophrenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Atypical neuroleptics may help reduce craving and relapses in this population. Future research should include more rigorous double-blind placebo-controlled studies with this class of medications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/070674370204700710","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T01:41:32Z","timestamp":1500514892000},"page":"671-675","source":"Crossref","is-referenced-by-count":82,"title":["Risperidone Decreases Craving and Relapses in Individuals with Schizophrenia and Cocaine Dependence"],"prefix":"10.1177","volume":"47","author":[{"given":"David A","family":"Smelson","sequence":"first","affiliation":[{"name":"Research Faculty, Department of Veterans Affairs, VISN 3 Mental Illness, Research, Education and Clinical Center, Lyons, New Jersey; Assistant Professor of Psychiatry, Department of Psychiatry, University of Medicine and Dentistry-Robert Wood Johnson Medical School, Piscataway, New Jersey; Assistant Professor of Psychiatry, Department of Psychiatry, University of Medicine Dentistry, New Jersey Medical School, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miklos F","family":"Losonczy","sequence":"additional","affiliation":[{"name":"Associate Clinical Director, Department of Veterans Affairs, VISN 3 Mental Illness, Research, Education and Clinical Center, Lyons, New Jersey; Associate Professor of Psychiatry, Department of Psychiatry, University of Medicine and Dentistry-Robert Wood Johnson Medical School, Piscataway, New Jersey; Associate Professor of Psychiatry, Department of Psychiatry, University of Medicine Dentistry, New Jersey Medical School, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig W","family":"Davis","sequence":"additional","affiliation":[{"name":"New Jersey Site Coordinator, Department of Veterans Affairs, VISN 3 Mental Illness, Research, Education and Clinical Center, Lyons, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"Kaune","sequence":"additional","affiliation":[{"name":"Research Faculty, Department of Veterans Affairs, VISN 3 Mental Illness, Research, Education and Clinical Center, Lyons, New Jersey; Assistant Professor of Psychiatry, Department of Psychiatry, University of Medicine and Dentistry-Robert Wood Johnson Medical School, Piscataway, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Williams","sequence":"additional","affiliation":[{"name":"Research Faculty, Department of Veterans Affairs, VISN 3 Mental Illness, Research, Education and Clinical Center, Lyons, New Jersey; Assistant Professor of Psychiatry, Department of Psychiatry, University of Medicine and Dentistry-Robert Wood Johnson Medical School, Piscataway, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Ziedonis","sequence":"additional","affiliation":[{"name":"Associate Professor of Psychiatry, Department of Psychiatry, University of Medicine and Dentistry-Robert Wood Johnson Medical School, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2002,9,1]]},"reference":[{"key":"bibr1-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450190043026"},{"key":"bibr2-070674370204700710","doi-asserted-by":"publisher","DOI":"10.3928\/0048-5713-19940901-10"},{"key":"bibr3-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/23.2.229"},{"key":"bibr4-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199402000-00008"},{"key":"bibr5-070674370204700710","first-page":"309","volume":"3","author":"Ziedonis DM","year":"1992","journal-title":"Psychopharmacology Bulletin"},{"key":"bibr6-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.152.10.1464"},{"key":"bibr7-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.148.11.1474"},{"key":"bibr8-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1016\/0893-133X(87)90004-2"},{"key":"bibr9-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1007\/BF02244907"},{"key":"bibr10-070674370204700710","doi-asserted-by":"publisher","DOI":"10.1081\/ADA-100103716"},{"key":"bibr11-070674370204700710","doi-asserted-by":"crossref","unstructured":"Smelson DA, Losonczy M, Kilker C, Starosta A, Kind J, Williams J, Ziedonis D. 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