{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:29:44Z","timestamp":1777519784249,"version":"3.51.4"},"reference-count":82,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T00:00:00Z","timestamp":1122854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can J Psychiatry"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To provide practical recommendations for monitoring patients both before and during treatment with atypical antipsychotics, to assist clinicians in implementing preventative measures against diabetes, and to establish baselines according to which clinicians should initiate diabetes treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>A working group of Canadian specialists in psychiatry and endocrinology reviewed peer-reviewed clinical studies published in this area and other relevant papers and abstracts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The reviewed studies further confirm that atypical antipsychotic medications are the most effective components in the medical management of many psychotic conditions; they also further emphasize the need to more stringently monitor and recognize diabetes risk factors inherent in these patients. Recommendations are based on a review of the available data, on expert opinion and consensus, and on current Canadian guidelines for the treatment of schizophrenia and management of diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients with psychiatric disorders, most particularly schizophrenia and mood disorders, have an increased risk for type 2 diabetes and should be screened frequently, especially when other risk factors are present. The resulting recommendations offer practical steps for effectively screening patients prior to and during treatment with atypical antipsychotics. They include 1) how to conduct an initial baseline assessment, 2) when and how to monitor blood glucose and lipid levels, and 3) how to educate patients regarding such lifestyle issues as nutrition, exercise, and diet.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/070674370505000909","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T21:50:07Z","timestamp":1483653007000},"page":"555-562","source":"Crossref","is-referenced-by-count":29,"title":["Atypical Antipsychotics in Psychiatric Practice: Practical Implications for Clinical Monitoring"],"prefix":"10.1177","volume":"50","author":[{"given":"Marie-Jos\u00e9e","family":"Poulin","sequence":"first","affiliation":[{"name":"Active Staff, Centre Hospitalier Affili\u00e9 Universitaire de Qu\u00e9bec, H\u00f4pital de l'Enfant-J\u00e9sus, Quebec, Quebec; Clinical Professor of Psychiatry, Universit\u00e9 Laval, Laval, Quebec; Clinical Director, Psychosis and the Perinatal Psychiatry Programs at Robert-Giffard Hospital, Quebec, Quebec"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Cortese","sequence":"additional","affiliation":[{"name":"Clinical Director, Windsor Regional Hospital, University of Western Ontario, Windsor, Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Williams","sequence":"additional","affiliation":[{"name":"Director, Royal Jubilee Hospital, Victoria, British Columbia; Clinical Professor, University of British Columbia, Victoria, British Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Wine","sequence":"additional","affiliation":[{"name":"Endocrinologist, Lifestyle Metabolism Centres, Thornhill, Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger S","family":"McIntyre","sequence":"additional","affiliation":[{"name":"Head, Mood Disorders Psychopharmacology Unit, University Health Network-Toronto Western Hospital, Toronto, Ontario; Assistant Professor of Psychiatry, University of Toronto, Toronto, Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,8,1]]},"reference":[{"key":"bibr1-070674370505000909","volume":"27","author":"Canadian Diabetes Association Clinical Practice Guidelines Expert Committee","year":"2003","journal-title":"Can J Diabetes"},{"key":"bibr2-070674370505000909","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.2.596"},{"key":"bibr3-070674370505000909","first-page":"113","volume":"29","author":"McIntyre RS","year":"2005","journal-title":"Can J Diabetes"},{"key":"bibr4-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1177\/07067437980430S201"},{"key":"bibr5-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.177.3.212"},{"key":"bibr6-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.176.1.76"},{"key":"bibr7-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291701005116"},{"key":"bibr8-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.53.7.874"},{"key":"bibr9-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)01000-2"},{"key":"bibr10-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1097\/00131746-200101000-00005"},{"key":"bibr11-070674370505000909","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4088\/JCP.v63n0104","volume":"63","author":"McIntyre RS","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"bibr12-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1177\/070674370104600308"},{"key":"bibr13-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.2.284"},{"key":"bibr14-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1007\/s001250050005"},{"key":"bibr15-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.4.337"},{"key":"bibr16-070674370505000909","first-page":"195","volume":"15","author":"Mukherjee S.","year":"1995","journal-title":"Schizophr Res"},{"key":"bibr17-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-440X(96)90054-1"},{"key":"bibr18-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.174.2.180b"},{"key":"bibr19-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a033504"},{"key":"bibr20-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1016\/0010-440X(80)90030-9"},{"key":"bibr21-070674370505000909","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1176\/ajp.156.9.1417","volume":"156","author":"Ahearn E","year":"1999","journal-title":"Am J Psychiatry"},{"key":"bibr22-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.16.1945"},{"key":"bibr23-070674370505000909","unstructured":"Raskin J. Nouveaux antipsychotiques atypiques et anomalies du m\u00e9tabolisme du glucose: Risque r\u00e9el ou exag\u00e9r\u00e9. Perspective Professionnelle 2001."},{"key":"bibr24-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.4.561"},{"key":"bibr25-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-977X(01)80358-8"},{"key":"bibr26-070674370505000909","volume-title":"Paper presented at the 39th Annual Meeting of the American College of Neuropsychopharmacology","author":"Gianfrancesco F","year":"2000"},{"key":"bibr27-070674370505000909","doi-asserted-by":"crossref","first-page":"28","DOI":"10.4088\/JCP.v66n0104","volume":"66","author":"McIntyre RS","year":"2005","journal-title":"J Clin Psychiatry"},{"key":"bibr28-070674370505000909","unstructured":"McIntyre RS, Konarski JZ. Bipolar disorder, overweight\/obesity, and disorders of glucose metabolism. Current Psychiatry 2005;Suppl:11\u201320."},{"key":"bibr29-070674370505000909","first-page":"111","volume":"29","author":"Woo V","year":"2005","journal-title":"Can J Diabetes"},{"key":"bibr30-070674370505000909","first-page":"122","volume":"29","author":"McIntyre RS","year":"2005","journal-title":"Can J Diabetes"},{"key":"bibr31-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1080\/10401230590932380"},{"key":"bibr32-070674370505000909","volume-title":"Paper presented at the American Psychiatric Association 53rd Institute on Psychiatric Services Convention","author":"Lage MJ","year":"2001"},{"key":"bibr33-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1097\/00045391-200309000-00007"},{"key":"bibr34-070674370505000909","volume-title":"Paper presented at the CPNP Annual Meeting","author":"Bellnier TJ","year":"2003"},{"key":"bibr35-070674370505000909","volume-title":"Paper presented at the American Psychiatric Association Annual Meeting","author":"Bellnier TJ","year":"2003"},{"key":"bibr36-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021884"},{"key":"bibr37-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.4.561"},{"key":"bibr38-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.4.518"},{"key":"bibr39-070674370505000909","first-page":"35","volume":"62","author":"Meltzer HY","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"bibr40-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a006969"},{"key":"bibr41-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801249"},{"key":"bibr42-070674370505000909","first-page":"31","volume":"60","author":"Blackburn GL","year":"1999","journal-title":"J Clin Psychiatry"},{"key":"bibr43-070674370505000909","volume-title":"Clinical guidelines on the identification, evaluation and treatment of overweight and obesity in adults (on-line)","year":"1998"},{"key":"bibr44-070674370505000909","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.1980.46.2.483"},{"key":"bibr45-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.136.3.287"},{"key":"bibr46-070674370505000909","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.1972.30.2.581"},{"key":"bibr47-070674370505000909","first-page":"256","volume":"49","author":"Ball MP","year":"2001","journal-title":"Schizophr Res"},{"key":"bibr48-070674370505000909","first-page":"519","volume":"28","author":"Cazenave M","year":"1967","journal-title":"Dis Nerv Syst"},{"key":"bibr49-070674370505000909","volume-title":"Behavioral weight reduction program for mentally handicapped persons: A self-control approach","author":"Fox R","year":"1981"},{"key":"bibr50-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.2.290"},{"key":"bibr51-070674370505000909","volume-title":"Managing metabolic concerns in patients with severe mental illness","author":"Keck PE","year":"2003"},{"key":"bibr52-070674370505000909","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v60n0402"},{"key":"bibr53-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/21.3.463"},{"key":"bibr54-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a033504"},{"key":"bibr55-070674370505000909","volume-title":"Presented at the National Institute of Mental Health, New Clinical Drug Evaluation Unit (NCDEU) 39th Annual Meeting","author":"Cavazzoni P.","year":"2001"},{"key":"bibr56-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105033441801"},{"key":"bibr57-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012512"},{"key":"bibr58-070674370505000909","unstructured":"Canada's Food Guide to Healthy Eating (on-line). Health Canada. Available: http:\/\/www.hc-sc.gc.ca\/hpfb-dgpsa\/onpp-bppn\/food_guide_rainbow_e.html. Accessed 2005 June 2."},{"key":"bibr59-070674370505000909","first-page":"921","volume":"169","author":"Fodor G","year":"2003","journal-title":"CMAJ"},{"key":"bibr60-070674370505000909","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.22.8.1266"},{"key":"bibr61-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1592\/phco.22.11.841.33629"},{"key":"bibr62-070674370505000909","first-page":"57","volume":"29","author":"Antochi R","year":"2004","journal-title":"J Psychiatry Neurosci"},{"key":"bibr63-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1177\/026988119801200309"},{"key":"bibr64-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1177\/070674370104600308"},{"key":"bibr65-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.6.854"},{"key":"bibr66-070674370505000909","first-page":"1","volume":"2","author":"Bleau PJ","year":"1999","journal-title":"Sant\u00e9 Mentale"},{"key":"bibr67-070674370505000909","doi-asserted-by":"publisher","DOI":"10.3109\/10401230209147397"},{"key":"bibr68-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.53.7.842"},{"key":"bibr69-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1177\/070674370104600610"},{"key":"bibr70-070674370505000909","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4088\/JCP.v62n0101","volume":"62","author":"Meltzer HY","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"bibr71-070674370505000909","first-page":"571","volume":"48","author":"Almeras N","year":"2001","journal-title":"Quebec Pharmacie"},{"key":"bibr72-070674370505000909","first-page":"20","volume":"60","author":"Ganguli R.","year":"1999","journal-title":"J Clin Psychiatry"},{"key":"bibr73-070674370505000909","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v60n0602"},{"key":"bibr74-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-200206000-00003"},{"key":"bibr75-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.156.11.1686"},{"key":"bibr76-070674370505000909","doi-asserted-by":"publisher","DOI":"10.1177\/070674370104600906"},{"key":"bibr77-070674370505000909","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v63n0306"},{"key":"bibr78-070674370505000909","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v63n0611"},{"key":"bibr79-070674370505000909","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v62n0614"},{"key":"bibr80-070674370505000909","first-page":"24","volume":"63","author":"Malhorta S","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"bibr81-070674370505000909","first-page":"33","volume":"63","author":"Aquila R.","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"bibr82-070674370505000909","volume-title":"Calculate your body mass index (on-line)"}],"container-title":["The Canadian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/070674370505000909","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/070674370505000909","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:09:36Z","timestamp":1777392576000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/070674370505000909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":82,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["10.1177\/070674370505000909"],"URL":"https:\/\/doi.org\/10.1177\/070674370505000909","relation":{},"ISSN":["0706-7437","1497-0015"],"issn-type":[{"value":"0706-7437","type":"print"},{"value":"1497-0015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}