{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T23:10:06Z","timestamp":1789859406415,"version":"4.0.1"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can J Psychiatry"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aimed to investigate the outcome of an 18-month randomized controlled trial (RCT) on subjective burden and psychopathology of patients suffering from schizophrenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>An RCT was used to compare hallucination-focused integrative treatment (HIT) and routine treatment (RT) in schizophrenia patients who persistently hear voices. We performed an intent-to-treat analysis on each of the 63 patients who were assessed at baseline, 9, and 18 months. On each of the 3 occasions, the differential effects of the treatment conditions were tested repeatedly. Sex, age, education, and illness (hallucination) duration were used as covariates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Patients in the experimental group retained improvements over time. Improvements in hallucinations, distress, and negative content of voices remained significant at the 5% level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>HIT seems to be an effective treatment strategy with long-lasting effects for treatment-refractory voice-hearing patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/070674370605100307","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T23:01:25Z","timestamp":1484089285000},"page":"169-177","source":"Crossref","is-referenced-by-count":22,"title":["\u201cHitting\u201d Voices of Schizophrenia Patients May Lastingly Reduce Persistent Auditory Hallucinations and Their Burden: 18-Month Outcome of a Randomized Controlled Trial"],"prefix":"10.1177","volume":"51","author":[{"given":"Jack A","family":"Jenner","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Psychiatry, University Medical Centre and Mental Health Care Foundation, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fokko J","family":"Nienhuis","sequence":"additional","affiliation":[{"name":"Senior Researcher, Department of Psychiatry, University Medical Centre and Mental Health Care Foundation, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"van de Willige","sequence":"additional","affiliation":[{"name":"Senior Researcher, Department of Psychiatry, University Medical Centre and Mental Health Care Foundation, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Durk","family":"Wiersma","sequence":"additional","affiliation":[{"name":"Professor, Department of Psychiatry, University Medical Centre, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2006,3,1]]},"reference":[{"key":"bibr1-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-7358(98)00007-5"},{"key":"bibr2-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.177.3.229"},{"key":"bibr3-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(02)00239-6"},{"key":"bibr4-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.186.4.324"},{"key":"bibr5-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1998.tb10103.x"},{"key":"bibr6-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2001.00189.x"},{"key":"bibr7-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2001.00213.x"},{"key":"bibr8-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2003.00102.x"},{"key":"bibr9-070674370605100307","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/oxfordjournals.schbul.a007058","volume":"30","author":"Jenner JA","year":"2004","journal-title":"Schizophr Bull"},{"key":"bibr10-070674370605100307","doi-asserted-by":"publisher","DOI":"10.1046\/j.0001-690X.2003.00237.x"},{"key":"bibr11-070674370605100307","volume-title":"WHO SCAN: Schedules for clinical assessment in neuropsychiatry","author":"World Health Organization","year":"1992"},{"key":"bibr12-070674370605100307","volume-title":"Practical statistics for medical research","author":"Altman DG","year":"1995"},{"key":"bibr13-070674370605100307","volume-title":"Coping training en cognitieve therapie bij schizofrenie patienten met chronische en invaliderende hallucinaties. 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