{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:45:24Z","timestamp":1777520724996,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can J Psychiatry"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To compare employment pay, count of infractions, and clinical symptoms in psychiatric inmates treated with clozapine or other antipsychotics after 6 months of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Clinical charts and institutional offence records of psychiatric inmates ( n = 98), comprised of those on clozapine ( n = 65) and on other antipsychotics ( n = 33), were reviewed at baseline and after 6 months of treatment. The outcome measures used were Brief Psychiatric Rating Scale (BPRS) scores, employment pay, medication compliance, and the frequency of institutional offences. A binary logistic regression model was used to analyze a categorical change in pay variable, while a negative binomial model was used to analyze the frequency of infractions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Treatment with clozapine was associated with greater odds of a pay increase (OR = 3.13; 95% CI 1.3 to 7.53, P= 0.01). However, patients on other antipsychotics had a more favourable improvement in BPRS ( F= 5.44, df = 1,57, P= 0.02). Patients on other antipsychotics also had a higher count of posttreatment offences (Incidence Rate Ratio = 2.22; 95% CI 1.11 to 4.41, P = 0.02).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Clozapine probably has a favourable effect on inmate behaviour and institutional adjustment. This effect can last up to 36 months after the initial dose.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/070674371005500108","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T19:42:51Z","timestamp":1484163771000},"page":"50-56","source":"Crossref","is-referenced-by-count":10,"title":["Does Clozapine Promote Employability and Reduce Offending among Mentally Disordered Offenders?"],"prefix":"10.1177","volume":"55","author":[{"given":"Lloyd","family":"Balbuena","sequence":"first","affiliation":[{"name":"Student, Institute of Cognitive Science, Carleton University, Ottawa, Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansfield","family":"Mela","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Psychiatry, University of Saskatchewan, Saskatoon, Saskatchewan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Wong","sequence":"additional","affiliation":[{"name":"Professor, Institute of Mental Health, Nottingham, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deqiang","family":"Gu","sequence":"additional","affiliation":[{"name":"Staff Statistician, Regional Psychiatric Centre\u2014Prairies, Saskatoon, Saskatchewan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olajide","family":"Adelugba","sequence":"additional","affiliation":[{"name":"Clinical Director, Regional Psychiatric Centre\u2014Prairies, Saskatoon, Saskatchewan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Tempier","sequence":"additional","affiliation":[{"name":"Professor, Department of Psychiatry, University of Saskatchewan, Saskatoon, Saskatchewan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,1,1]]},"reference":[{"key":"bibr1-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1994.tb05837.x"},{"issue":"8","key":"bibr2-070674371005500108","first-page":"892","volume":"41","author":"Meltzer HY","year":"1990","journal-title":"Hosp Community Psychiatry"},{"key":"bibr3-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.4.518"},{"key":"bibr4-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1988.01800330013001"},{"key":"bibr5-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-9964(00)00016-5"},{"key":"bibr6-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.156.1.79"},{"key":"bibr7-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.2006.163.4.600"},{"key":"bibr8-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbj067"},{"key":"bibr9-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1992.01820060056009"},{"issue":"7","key":"bibr10-070674371005500108","first-page":"761","volume":"41","author":"Swanson JW","year":"1990","journal-title":"Hosp Community Psychiatry"},{"key":"bibr11-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.07061013"},{"issue":"4","key":"bibr12-070674371005500108","first-page":"607","volume":"23","author":"Buckley P","year":"1995","journal-title":"Bull Am Acad Psychiatry Law"},{"key":"bibr13-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.1.82"},{"key":"bibr14-070674371005500108","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.17.1.36"},{"issue":"6","key":"bibr15-070674371005500108","first-page":"821","volume":"152","author":"Meltzer HY","year":"1995","journal-title":"Clozapine: Is another view valid? 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