{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:44:09Z","timestamp":1777520649980,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Can J Psychiatry"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Psychiatric comorbidities are common among psychiatric patients and typically associated with poorer clinical prognoses. Subjects of a large Danish birth cohort were used to study the relation between mortality and co-occurring psychiatric diagnoses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>We searched the Danish Central Psychiatric Research Registry for 8109 birth cohort members aged 45 years. Lifetime psychiatric diagnoses (International Classification of Diseases, Revision 10, group F codes, Mental and Behavioural Disorders, and one Z code) for identified subjects were organized into 14 mutually exclusive diagnostic categories. Mortality rates were examined as a function of number and type of co-occurring diagnoses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Psychiatric outcomes for 1247 subjects were associated with 157 deaths. Early mortality risk in psychiatric patients correlated with the number of diagnostic categories (Wald \u00d7\n                      <jats:sup>2<\/jats:sup>\n                      = 25.0, dl = 1, P &lt; 0.001). This global relation was true for anxiety and personality disorders, but not for schizophrenia and substance abuse, which had intrinsically high mortality rates with no comorbidities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Risk of early mortality among psychiatric patients appears to be a function of both the number and the type of psychiatric diagnoses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/070674371205700809","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T09:56:06Z","timestamp":1500544566000},"page":"505-511","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Forty-Five-Year Mortality Rate as a Function of the Number and Type of Psychiatric Diagnoses Found in a Large Danish Birth Cohort"],"prefix":"10.1177","volume":"57","author":[{"given":"Wendy","family":"Madarasz","sequence":"first","affiliation":[{"name":"Data Analyst, Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Manzardo","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik Lykke","family":"Mortensen","sequence":"additional","affiliation":[{"name":"Professor, Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Penick","sequence":"additional","affiliation":[{"name":"Professor, Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Knop","sequence":"additional","affiliation":[{"name":"Senior Research Fellow, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Sorensen","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Psychiatry, Copenhagen University Hospital, Copenhagen, Denmark; Consulting Psychiatrist, Amager Hospital, Capital Region of Denmark, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrik","family":"Becker","sequence":"additional","affiliation":[{"name":"Adjunct Professor, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark; Chief Physician, Department of Medical Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Nickel","sequence":"additional","affiliation":[{"name":"Statistical Data Coordinator, Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"William","family":"Gabrielli","sequence":"additional","affiliation":[{"name":"Professor, Chairman, Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,8,1]]},"reference":[{"key":"bibr1-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1985.01790240049005"},{"key":"bibr2-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1176\/ps.2006.57.10.1474"},{"key":"bibr3-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2004.00393.x"},{"key":"bibr4-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2006.00728.x"},{"issue":"1","key":"bibr5-070674371205700809","first-page":"39","volume":"27","author":"Rehm J","year":"2003","journal-title":"Alcohol Res Health"},{"key":"bibr6-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1007\/BF02287340"},{"key":"bibr7-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1977.01770220019001"},{"key":"bibr8-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709005790"},{"key":"bibr9-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.173.1.11"},{"key":"bibr10-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2009.08.017"},{"key":"bibr11-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-6-44"},{"key":"bibr12-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181eb33e9"},{"key":"bibr13-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1985.01790240060006"},{"key":"bibr14-070674371205700809","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-9-127"},{"key":"bibr15-070674371205700809","volume-title":"Health care systems in transition [Internet]","author":"Vallg\u00e5rda S","year":"2001"},{"key":"bibr16-070674371205700809","first-page":"82","volume":"44","author":"Munk-J\u00f8rgensen P","year":"1997","journal-title":"Dan Med Bull"},{"key":"bibr17-070674371205700809","unstructured":"Zachau-Christiansen B. 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