{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:31:07Z","timestamp":1777519867823,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1982,4,1]],"date-time":"1982-04-01T00:00:00Z","timestamp":386467200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can J Psychiatry"],"published-print":{"date-parts":[[1982,4]]},"abstract":"<jats:p>Three cases of orgasmic inhibition by clomipramine are reported, one in a male and two infernales. All were depressed patients with obsessive-compulsive features. Orgasmic dysfunction manifested shortly after beginning clomipramine therapy despite a return of libido as the depression lifted. Two of these patients switched to desipramine which led to a resolution of sexual dysfunction while maintaining the patients depression free. The third patient manipulated dosage times to diminish the orgastic problem.<\/jats:p>\n                  <jats:p>Strong anticholinergic and\/or anti-adrenergic properties of clomipramine are suspected to underlie the development of this problem.<\/jats:p>","DOI":"10.1177\/070674378202700311","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T04:51:49Z","timestamp":1493182309000},"page":"228-231","source":"Crossref","is-referenced-by-count":20,"title":["Sexual Dysfunction and Clomipramine"],"prefix":"10.1177","volume":"27","author":[{"given":"Keith C.","family":"Quirk","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Dalhousie University, Halifax, N.S."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas R.","family":"Einarson","sequence":"additional","affiliation":[{"name":"Community Pharmacist, McKenzie's Pharmacy, Wiarton, Ontario."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1982,4,1]]},"reference":[{"key":"bibr1-070674378202700311","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-197918030-00003"},{"key":"bibr2-070674378202700311","volume-title":"Disorders of sexual desire.","author":"Kaplan H.S.","year":"1977"},{"key":"bibr3-070674378202700311","volume-title":"The new sex therapy.","author":"Kaplan H.S.","year":"1974"},{"key":"bibr4-070674378202700311","first-page":"21","volume":"14","author":"Nestoros J.N.","year":"1979","journal-title":"Int Drug Ther Newsletter"},{"key":"bibr5-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-196609000-00006"},{"key":"bibr6-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.135.6.750"},{"key":"bibr7-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.133.1.82"},{"key":"bibr8-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.136.9.1200"},{"key":"bibr9-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.136.1.124b"},{"key":"bibr10-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.136.12.1616-b"},{"key":"bibr11-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.136.3.350a"},{"key":"bibr12-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1177\/070674377301800510"},{"key":"bibr13-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.136.1.1"},{"key":"bibr14-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.136.2.161"},{"key":"bibr15-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.122.6.719"},{"key":"bibr17-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1977212201"},{"key":"bibr18-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1977.01770140126014"},{"key":"bibr19-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.135.6.722"},{"key":"bibr20-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1192\/S000712500019292X"},{"key":"bibr21-070674378202700311","first-page":"86","volume-title":"Somatic manifestations of depressive disorders.","author":"Renshaw D.C.","year":"1974"},{"key":"bibr22-070674378202700311","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1974.01760130040006"}],"container-title":["The Canadian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/070674378202700311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/070674378202700311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:09:48Z","timestamp":1777392588000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/070674378202700311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,4]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1982,4]]}},"alternative-id":["10.1177\/070674378202700311"],"URL":"https:\/\/doi.org\/10.1177\/070674378202700311","relation":{},"ISSN":["0706-7437","1497-0015"],"issn-type":[{"value":"0706-7437","type":"print"},{"value":"1497-0015","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,4]]}}}