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None of the patients returned to a pre-drug level of activity. The effect of phenobarbital on the reticular system is discussed. It is important for clinicians to carefully consider the potential side-effects of the use of phenobarbital in children in whom overactivity is a problem. Ascertaining whether hyperactivity has been caused or exacerbated by exposure to phenobarbital may be important in the differential diagnosis of hyperactivity.<\/jats:p>","DOI":"10.1177\/070674378703200104","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T04:27:54Z","timestamp":1493180874000},"page":"10-13","source":"Crossref","is-referenced-by-count":17,"title":["Does the Use of Phenobarbital as an Anticonvulsant Permanently Exacerbate Hyperactivity?"],"prefix":"10.1177","volume":"32","author":[{"given":"Larry","family":"Burd","sequence":"first","affiliation":[{"name":"Child Evaluation and Treatment Program, Medical Center Rehabilitation Hospital Grand Forks, North Dakota"},{"name":"Departments of Neurology and Pediatrics, University of North Dakota School of Medicine, Grand Forks, North Dakota"},{"name":"The Center for Teaching and Learning, University of North Dakota, Grand Forks, North Dakota."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Kerbeshian","sequence":"additional","affiliation":[{"name":"University of North Dakota School of Medicine, Grand Forks, North Dakota."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne","family":"Fisher","sequence":"additional","affiliation":[{"name":"Grafton State School, Grafton, North Dakota."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,2,1]]},"reference":[{"key":"bibr1-070674378703200104","author":"Burd L.","journal-title":"Can J Psychiatry"},{"key":"bibr2-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.12.1210"},{"key":"bibr3-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/91.2.197"},{"key":"bibr4-070674378703200104","volume-title":"Modern trends in neurology.","author":"Reynolds E.H.","year":"1970"},{"key":"bibr5-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-8123-5_3"},{"key":"bibr6-070674378703200104","first-page":"177","volume":"18","author":"Tomlinson L.L.","year":"1982","journal-title":"Br J Clin Pract"},{"key":"bibr7-070674378703200104","volume-title":"Adverse effects of antiepileptic drugs.","author":"Schmidt D.","year":"1982"},{"key":"bibr8-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1981.tb01313.x"},{"key":"bibr9-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.46.3.227"},{"key":"bibr10-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(84)90036-5"},{"key":"bibr11-070674378703200104","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(74)90013-2"}],"container-title":["The Canadian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/070674378703200104","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/070674378703200104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:08:33Z","timestamp":1777392513000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/070674378703200104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,2]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,2]]}},"alternative-id":["10.1177\/070674378703200104"],"URL":"https:\/\/doi.org\/10.1177\/070674378703200104","relation":{},"ISSN":["0706-7437","1497-0015"],"issn-type":[{"value":"0706-7437","type":"print"},{"value":"1497-0015","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,2]]}}}