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Cautious initiation of testosterone replacement therapy to our patient was associated with sexual maturation and, interestingly enough, disappearance of his longstanding aggressive fantasies and behaviors towards females. An explanatory hypothesis is proposed and clues for early detection of the syndrome are suggested.<\/jats:p>","DOI":"10.1177\/070674378803300912","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T04:23:51Z","timestamp":1493180631000},"page":"846-850","source":"Crossref","is-referenced-by-count":23,"title":["Testosterone Treatment of an XXYY Male Presenting with Aggression: A Case Report"],"prefix":"10.1177","volume":"33","author":[{"given":"Nabil","family":"Sourial","sequence":"first","affiliation":[{"name":"McGill University, Montreal, Quebec; The Montreal General Hospital, Montreal, Quebec; Douglas Hospital, Montreal, Quebec"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Fenton","sequence":"additional","affiliation":[{"name":"The Montreal General Hospital, Montreal, Quebe; St. Mary's Hospital Centre, Montreal, 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