{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T04:35:36Z","timestamp":1777782936663,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Appl Gerontol"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>This study aimed to examine the institutionalization rate in patients with dementia in Taiwan, identify the predictors of institutionalization, and conduct a mediation analysis of caregiver burden between neuropsychiatric symptoms and institutionalization. We analyzed data from a retrospective cohort registered in dementia collaborative care ( N = 518). The analyses applied univariate and multivariate Cox proportional hazard regression with Firth\u2019s penalized likelihood to assess the relationship between each predictor at entry and institutionalization for survival analysis. Thirty (5.8%) patients were censored due to institutionalization after a median follow-up of one-and-a-half years. Neuropsychiatric symptoms, loss of walking ability, and living alone predicted institutionalization. Caregiver burden may partially mediate the effects of neuropsychiatric symptoms and institutionalization. High caregiver burden due to presence of neuropsychiatric symptoms may partially contribute to institutionalization among people living with dementia in Taiwan. However, proper management of neuropsychiatric symptoms and caregiver empowerment may ameliorate institutionalization risk.<\/jats:p>","DOI":"10.1177\/07334648211073129","type":"journal-article","created":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T23:50:00Z","timestamp":1646005800000},"page":"1357-1364","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Prediction of Institutionalization for Patients With Dementia in Taiwan According to Condition at Entry to Dementia Collaborative Care"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2549-6762","authenticated-orcid":false,"given":"Yen-Jen","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Changhua Christian Hospital, Changhua, Taiwan"},{"name":"Department of Psychiatry, Yuanlin Christian Hospital, Changhua, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Fu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan"},{"name":"Department of Holistic Wellness, Ming Dao University, Changhua, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Ming","family":"Jhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Che","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Changhua Christian Hospital, Changhua, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Chen","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Changhua Christian Hospital, Changhua, Taiwan"},{"name":"School of Medicine, Chung Shan Medical University, Taichung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3876-6143","authenticated-orcid":false,"given":"Yi-Cheng","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Changhua Christian Hospital, Changhua, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,2,27]]},"reference":[{"key":"bibr1-07334648211073129","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00371-1"},{"key":"bibr2-07334648211073129","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.008"},{"key":"bibr3-07334648211073129","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/41.5.652"},{"key":"bibr4-07334648211073129","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-131850"},{"key":"bibr5-07334648211073129","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.299.6712.1375"},{"issue":"2","key":"bibr6-07334648211073129","first-page":"193","volume":"25","author":"Caron C. 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