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During an evolving pandemic that jeopardizes employment and housing, assessing the relationship between ADRD and homelessness is critical since the latter is potentially intervenable. The objective of this study is to review the literature and determine whether there is an association between homelessness and dementia risk. A systematic review of existing studies was conducted through PubMED, SCOPUS, and EMBASE among others. Of the 228 results found, nine met inclusion criteria. Homeless studies mainly centered on veteran populations ( n = 6\/9). There is a complex relationship suggesting homelessness as a risk for and consequence of ADRD but also co-occurrence with psychiatric disorders, substance abuse, and traumatic injuries. Future studies should employ enumeration surveys with modular longitudinal tracking and measure social determinants of health, discrimination, chronic stress, and mood disorders.<\/jats:p>","DOI":"10.1177\/07334648221109747","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T21:07:02Z","timestamp":1656104822000},"page":"2404-2413","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Associations between Homelessness and Alzheimer\u2019s Disease and Related Dementia: A Systematic Review"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7966-3509","authenticated-orcid":false,"given":"Ganesh M.","family":"Babulal","sequence":"first","affiliation":[{"name":"Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA"},{"name":"Institute of Public Health, Washington University in St. Louis, St. Louis, MO, USA"},{"name":"Department of Psychology, Faculty of Humanities, University of Johannesburg, South Africa"},{"name":"Department of Clinical Research and Leadership, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology, University of California Santa Barbara, Santa Barbara, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3618-449X","authenticated-orcid":false,"given":"Paris","family":"Adkins-Jackson","sequence":"additional","affiliation":[{"name":"School of Nursing, Johns Hopkins University, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C.","family":"Pearson","sequence":"additional","affiliation":[{"name":"Peter & Paul Community Services, St. Louis, MO, USA"},{"name":"Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique M.","family":"Williams","sequence":"additional","affiliation":[{"name":"Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO, USA"},{"name":"New Horizons PACE, St. Louis, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,24]]},"reference":[{"key":"bibr1-07334648221109747","doi-asserted-by":"publisher","DOI":"10.26419\/int.00049.001"},{"key":"bibr2-07334648221109747","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12328"},{"key":"bibr3-07334648221109747","volume-title":"42 U.S. Code \u00a7 11302\u2014general definition of homeless individual","author":"Anonymous"},{"key":"bibr4-07334648221109747","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30569-X"},{"key":"bibr5-07334648221109747","doi-asserted-by":"publisher","DOI":"10.1176\/ps.2009.60.3.398"},{"key":"bibr6-07334648221109747","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000534"},{"key":"bibr7-07334648221109747","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.0860"},{"key":"bibr8-07334648221109747","author":"Fessler P.","year":"2021","journal-title":"NPR"},{"key":"bibr9-07334648221109747","author":"Flaming D.","year":"2021","journal-title":"Economic Roundtable"},{"issue":"1","key":"bibr10-07334648221109747","first-page":"17","volume":"5","author":"Garrett D. 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