{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:15:59Z","timestamp":1786115759123,"version":"build-2736575974"},"reference-count":54,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K99AG078286"],"award-info":[{"award-number":["K99AG078286"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K01MH115794"],"award-info":[{"award-number":["K01MH115794"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R34MH137775"],"award-info":[{"award-number":["R34MH137775"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Appl Gerontol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    Studies assessing depression as a mediating factor between adverse childhood experiences (ACEs) and subjective cognitive decline (SCD) are lacking. Therefore, the aims of this study were to: (1) determine the mediating role of depression in the association between ACEs and SCD; and (2) assess the moderating role of gender. Data were obtained from the 2023 Behavioral Risk Factor Surveillance Study (BRFSS) survey (\n                    <jats:italic toggle=\"yes\">N<\/jats:italic>\n                    = 38,600). Crude and adjusted path analyses were used to determine the mediating role of depression between ACEs and SCD. Adjusted analyses controlled for sociodemographic confounders. ACEs were positively associated with depression (B = 0.129,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.001), depression was positively associated with SCD (B = 0.224,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.001), and ACEs were positively associated with SCD (B = 0.066,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.001). Depression mediated the association between ACEs and SCD in the overall population (B = 0.029,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.001), and for men (B = 0.025,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.001) and women (B = 0.032,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; 0.001). Intervention programs addressing ACEs may reduce depression and help with cognition for men and women.\n                  <\/jats:p>","DOI":"10.1177\/07334648251386108","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T11:35:57Z","timestamp":1759750557000},"page":"1772-1779","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Adverse Childhood Experiences, Depression and Subjective Cognitive Decline by Gender: A Moderated Mediation Analysis"],"prefix":"10.1177","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9552-244X","authenticated-orcid":false,"given":"Monique J.","family":"Brown","sequence":"first","affiliation":[{"name":"University of South Carolina"},{"name":"University of South Carolina"},{"name":"University of South Carolina"},{"name":"University of South Carolina"},{"name":"University of the Free State"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9214-5677","authenticated-orcid":false,"given":"Darlingtina K.","family":"Esiaka","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Medicine"},{"name":"University of Kentucky College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaya","family":"Viswanathan","sequence":"additional","affiliation":[{"name":"Independent Researcher"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,6]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.13027"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.17.1652"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2006.8.2\/fbenazzi"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2014.05.009"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paed.2017.12.008"},{"issue":"10","key":"e_1_3_6_7_1","doi-asserted-by":"crossref","first-page":"733464823117529","DOI":"10.1177\/07334648231175299","article-title":"Childhood sexual trauma and subjective cognitive decline: An assessment of racial\/ethnic and sexual orientation disparities","volume":"42","author":"Brown M. J.","year":"2023","unstructured":"Brown M. J., Amoatika D., Addo P. N. O., Kaur A., Haider M. R., Merrell M. A., Crouch E. (2023). Childhood sexual trauma and subjective cognitive decline: An assessment of racial\/ethnic and sexual orientation disparities. Journal of Applied Gerontology: The Official Journal of the Southern Gerontological Society, 42(10), 7334648231175299. https:\/\/doi.org\/10.1177\/07334648231175299","journal-title":"Journal of Applied Gerontology: The Official Journal of the Southern Gerontological Society"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2020.1861214"},{"issue":"15","key":"e_1_3_6_9_1","first-page":"886260521101522","article-title":"Disparities by gender and race\/ethnicity in child maltreatment and memory performance","volume":"37","author":"Brown M. J.","year":"2021","unstructured":"Brown M. J., Jiang Y., Hung P., Haider M. R., Crouch E. (2021). Disparities by gender and race\/ethnicity in child maltreatment and memory performance. Journal of Interpersonal Violence, 37(15-16), 8862605211015222. https:\/\/doi.org\/10.1177\/08862605211015222","journal-title":"Journal of Interpersonal Violence"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.3928\/00989134-20220110-01"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/07334648211058718"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-190869"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2015.02.044"},{"key":"e_1_3_6_14_1","unstructured":"Centers for Disease Control and Prevention. (2024). The behavioral risk factor surveillance system. 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