{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:28:39Z","timestamp":1777922919890,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicol Ind Health"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:p>The plant Mentha spicata, or peppermint, is commonly used in the treatment of loss of appetite, common cold, bronchitis, sinusitis, fever, nausea and vomiting, and indigestion as a herbal agent. In this study, we aimed to investigate the biochemical and histological effects of M. spicata Labiatae, growing on the Anamas high plateau of Yenisarbademli town, on rat uterine tissue. Twenty female Wistar albino rats weighing 160\u00b110 g were used for this study. Rats were divided into two groups of ten animals: group I received no herbal tea (control group) and group II received 20 g\/L M. spicata tea. Control group rats were given commercial drinking water (Hayat DANONESA water). Herbal tea was prepared daily and provided at all times to the rats over 30 days as drinking water. Plasma malondialdehyde (MDA) levels were determined. In addition, uterine tissues were submitted for histopathologic examination. MDA levels were increased in group II when compared with the control group. The difference between group II and the control group was statistically significant ( P &lt; 0.01). In the M. spicata Labiatae-treated group, histopathological changes like apoptosis and diffuse eosinophil leucocyte infiltration in surface and stromal glandular epithelium were observed in both endometrium and endocervix. It was concluded that lipid peroxidation and uterine damage occurs after M. spicata administration in rat uterus. Despite the beneficial effects of M. spicata Labiatae in indigestion, we should also be aware of the toxic effects when it is not used in the recommended fashion, at the recommended dose.<\/jats:p>","DOI":"10.1177\/0748233706071738","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T02:53:36Z","timestamp":1484535216000},"page":"343-348","source":"Crossref","is-referenced-by-count":14,"title":["The effect of\n                    <i>Mentha spicata<\/i>\n                    Labiatae on uterine tissue in rats"],"prefix":"10.1177","volume":"22","author":[{"given":"Mehmet","family":"G\u00fcney","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine,                         S\u00fcleyman Demirel University, Isparta, Turkey,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baha","family":"Oral","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine,                         S\u00fcleyman Demirel University, Isparta, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nermin","family":"Karahanli","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine, S\u00fcleyman Demirel                         University, Isparta, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer","family":"Mungan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine,                         S\u00fcleyman Demirel University, Isparta, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Akdogan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Clinical Biochemistry, Faculty of                         Medicine, S\u00fcleyman Demirel University, Isparta, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1191\/0960327103ht332oa"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.03.046"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1191\/0960327104ht412oa"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(01)00591-3"},{"key":"atypb5","first-page":"2102","volume":"32","author":"Aslan, R.","year":"1997","journal-title":"Journal of Environmental Science and Health A"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.17660\/ActaHortic.1993.333.27"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.34.020183.000415"},{"key":"atypb8","unstructured":"Foster, S. 1996: Herbs for your health.                      Interweave Press                 , 72-73."},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1994.014003228.x"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114599000537"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1126\/science.8235659"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-13-05089.1997"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)90191-X"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1007\/BF02936952"},{"key":"atypb15","first-page":"57","volume-title":"Congress and workshop of clinical and experimental research. Course Handbook","author":"Okur, H."},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.00343.x"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1079\/NRR19960016"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6194.835"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(69)80061-2"},{"key":"atypb20","first-page":"24","volume":"16","author":"Starburck, J. J.","year":"2001","journal-title":"Men\u2019s Health"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)83557-7"},{"key":"atypb22","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0944-7113(96)80070-5","volume":"2","author":"Westphal, J.","year":"1996","journal-title":"Phytomedicine"},{"key":"atypb23","unstructured":"Wichtl, M. 1994: Herbal drugs and phytopharmaceuticals.                      CRC Press                 , 336-338."},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(95)90060-8"},{"key":"atypb25","unstructured":"Zarrow, M. X.                 ,                      Yochia, J. M.                  and                      McCarthy, J. J. 1964: Experimental endocrinology: a source book of basic                 techniques.                      Academic Press                 , 36-39."}],"container-title":["Toxicology and Industrial Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0748233706071738","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0748233706071738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:33:40Z","timestamp":1777667620000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0748233706071738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1177\/0748233706071738"],"URL":"https:\/\/doi.org\/10.1177\/0748233706071738","relation":{},"ISSN":["0748-2337","1477-0393"],"issn-type":[{"value":"0748-2337","type":"print"},{"value":"1477-0393","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}