{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:30:17Z","timestamp":1777923017336,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T00:00:00Z","timestamp":1319673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Toxicol Ind Health"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p>Listerine (LN) is one of the most commonly used mouth rinses worldwide although very limited information is available concerning its genotoxicity. In another view, the biological safety profile of oral care products is frequently assumed on the basis of simplistic test models. Therefore, the present study was undertaken to investigate the in vitro genotoxic potential of LN using micronucleus and single cell gel electrophoresis tests as genetic endpoints. Different concentrations of LN (0\u2013100% of ml\/culture, v\/v) were applied to whole human blood cultures ( n = 5). The result of the present study showed that there were no statistically significant differences ( p &gt; 0.05) between the control group and the groups treated with LN alone in both analysed endpoints. In conclusion, our result first demonstrated the absence of genotoxicity of LN on human lymphocytes.<\/jats:p>","DOI":"10.1177\/0748233711410918","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T20:38:39Z","timestamp":1319747919000},"page":"271-275","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of genotoxicity after application of Listerine\n                    <sup>\u00ae<\/sup>\n                    on human lymphocytes by micronucleus and single cell gel electrophoresis assays"],"prefix":"10.1177","volume":"28","author":[{"given":"Hasan","family":"T\u00fcrkez","sequence":"first","affiliation":[{"name":"Faculty of Science, Department of Biology, Atat\u00fcrk University, Erzurum, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ba\u015fak","family":"To\u011far","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology, Atat\u00fcrk University, Erzurum, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taner","family":"Arabac\u0131","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Department of Periodontology, Atat\u00fcrk University, Erzurum, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,10,27]]},"reference":[{"key":"bibr1-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290512.x"},{"key":"bibr2-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2009.02.008"},{"key":"bibr3-0748233711410918","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2003.0322"},{"key":"bibr4-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1080\/01480540600653093"},{"key":"bibr5-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2010.06.004"},{"key":"bibr6-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/S0027-5107(00)00065-8"},{"key":"bibr7-0748233711410918","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.38929"},{"key":"bibr8-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1161(75)90082-5"},{"key":"bibr9-0748233711410918","first-page":"44","volume":"27","author":"Horvathova E","year":"2006","journal-title":"Neuroendocrinology Letters"},{"key":"bibr10-0748233711410918","doi-asserted-by":"publisher","DOI":"10.2144\/99275bm10"},{"key":"bibr11-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2008.08.012"},{"key":"bibr12-0748233711410918","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1985.0422"},{"key":"bibr13-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1042\/BST0370914"},{"key":"bibr14-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2008.11.015"},{"key":"bibr15-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/0887-2333(91)90010-B"},{"key":"bibr16-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080610"},{"key":"bibr17-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/0887-2333(91)90010-B"},{"key":"bibr18-0748233711410918","unstructured":"Pfizer Material Safety Data Sheet (2001) WL018 - Listerine\n                      \u00ae\n                      Antiseptic-Coolmint."},{"key":"bibr19-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2004.00759.x"},{"key":"bibr20-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.07.010"},{"key":"bibr21-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1002\/em.20332"},{"issue":"1","key":"bibr22-0748233711410918","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1081\/DCT-100103086","volume":"24","author":"Saleha Banu B","year":"2001","journal-title":"Drug and Chemical Toxicology"},{"issue":"6","key":"bibr23-0748233711410918","first-page":"404","volume":"19","author":"Shulman JD","year":"1997","journal-title":"Pediatric Dentistry"},{"key":"bibr24-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(88)90265-0"},{"key":"bibr25-0748233711410918","doi-asserted-by":"publisher","DOI":"10.1177\/0748233710375951"},{"key":"bibr26-0748233711410918","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2006.0406"},{"key":"bibr27-0748233711410918","unstructured":"Songwattana S (2003) The effects of mouthwash on micronucleus formation in human buccal epithelial cells and KB cell line. 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