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All the subjects underwent medical examinations, which investigated particularly the presence of clinical signs compatible with zoonoses, and routine blood tests from venous blood sample, which tested previous immunisation versus cited microorganisms and serum concentration of Cu, Se, and Mn. The subjects were divided according to IgG positivity versus the cited microorganisms. The group of subjects with IgG positive versus Brucella showed statistically significant higher Cu levels than controls, while the Mn levels were not; the group of subjects with IgG positive versus Rickettsia showed higher levels of all three tested metals. The concentration of the examined metals did not show statistically significant difference between IgG-positive subjects versus subjects with Borrelia compared to controls. These data could confirm the role of both Cu and Se \u00a0in the regulation of immune response.<\/jats:p>","DOI":"10.1177\/0748233712445050","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T22:27:03Z","timestamp":1335824823000},"page":"737-745","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Serum levels of copper, selenium and manganese in forestry workers testing IgG positive for\n                    <i>Brucella<\/i>\n                    ,\n                    <i>Borrelia<\/i>\n                    , and\n                    <i>Rickettsia<\/i>"],"prefix":"10.1177","volume":"29","author":[{"given":"Simona","family":"Abbate","sequence":"first","affiliation":[{"name":"Dipartimento di Medicina Sociale del Territorio, Sezione Medicina del Lavoro, Universit\u00e0 degli Studi di Messina, Messina, 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