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They are also integral components of gasoline, distillate fuels and other petroleum products. These substituted aromatics are economically important in the chemical, petroleum, pharmaceutical, polymer, paint and dye industries. Alkylbenzenes such as toluene, xylene, ethylbenzene, styrene and cumene are toxicologically important since they are produced, used or disposed of in the largest quantities and therefore might pose significant and potential health risks to man and the environment. In general, the toxicity of alkylbenzenes has been found to be relatively low. Also, for the most part, human and environmental risks are low; however, there may be a few operations where the potential for high exposure could exist. These exposures are minimized by workplace controls or personal protective equipment. Furthermore, health risks for humans are minimized by guidelines for maximum allowable exposure concentrations which have been established for the workplace. This present paper reviews the toxicology and disposition of toluene in animals and humans.<\/jats:p>","DOI":"10.1177\/074823378800400105","type":"journal-article","created":{"date-parts":[[2013,9,9]],"date-time":"2013-09-09T18:31:23Z","timestamp":1378751483000},"page":"49-75","source":"Crossref","is-referenced-by-count":58,"title":["Health Effects of the Alkylbenzenes. I. Toluene"],"prefix":"10.1177","volume":"4","author":[{"given":"Awrence K.","family":"Low","sequence":"first","affiliation":[{"name":"Environmental and Health Sciences Laboratory Mobil Oil Corporation Princeton, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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