{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:46:25Z","timestamp":1777790785893,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2010,9,28]],"date-time":"2010-09-28T00:00:00Z","timestamp":1285632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biol Rhythms"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>In the absence of the entraining light-dark cycle, most totally blind humans free-run, albeit with relative coordination to nonphotic zeitgebers. Such blind free-runners (BFRs) often attempt to maintain a 24-h sleep-wake schedule and consequently suffer from recurrent sleep disruption and daytime somnolence. This study was conducted to determine the periods of the free-running melatonin rhythm and of the rest-activity cycle in 16 BFRs. It was found that the non-24-h component of the rest-activity rhythm correlated with the observed period of the circadian pacemaker.<\/jats:p>","DOI":"10.1177\/0748730410379080","type":"journal-article","created":{"date-parts":[[2010,9,28]],"date-time":"2010-09-28T13:13:16Z","timestamp":1285679596000},"page":"381-384","source":"Crossref","is-referenced-by-count":15,"title":["Rest-Activity Cycle and Melatonin Rhythm in Blind Free-Runners Have Similar Periods"],"prefix":"10.1177","volume":"25","author":[{"given":"Jonathan","family":"Emens","sequence":"first","affiliation":[{"name":"Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health & Science University, Portland, OR,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred J.","family":"Lewy","sequence":"additional","affiliation":[{"name":"Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health & Science University, Portland, OR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber L.","family":"Laurie","sequence":"additional","affiliation":[{"name":"Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health & Science University, Portland, OR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannie B.","family":"Songer","sequence":"additional","affiliation":[{"name":"Sleep and Mood Disorders Laboratory, Department of Psychiatry, Oregon Health & Science University, Portland, OR"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9,28]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5423.2177"},{"key":"atypb2","first-page":"A62","volume":"29","author":"Emens J.","year":"2006","journal-title":"Sleep"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1177\/0748730404273294"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1177\/0748730403256796"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/16.4.333"},{"key":"atypb6","unstructured":"Klerman EB ( 2001) Non-photic effects on the circadian system: results from experiments in blind and sighted individuals. 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