{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:46:21Z","timestamp":1777790781798,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1996,9,1]],"date-time":"1996-09-01T00:00:00Z","timestamp":841536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Biol Rhythms"],"published-print":{"date-parts":[[1996,9]]},"abstract":"<jats:p>The effects of calmodulin antagonists and inhibitors of protein kinases and phosphatases on light-induced phase shifting were investigated in Neurospora crassa. Calmodulin antagonists, namely, trifluoperazine, chlorpromazine, and W-7, almost completely inhibited the light-induced phase shifting without having any effect on the circadian clock itself. Chlorpromazine was less effective in inhibiting the light-induced phase shifting than trifluoperazine. W-5, a dechlorinated analogue of W-7, failed to inhibit the light-induced phase shifting at the same concentration as that at which W-7 was effective. These results suggest that calmodulin is required during signal transduction from the light-perceiving system to the circadian clock in N. crassa. Inhibitors of protein phosphorylation did not inhibit the light-induced phase shifting, although these inhibitors completely inhibited mycelial growth. Trifluoperazine partially inhibited the phosphorylation of three proteins when phosphorylation was assayed in vitro.<\/jats:p>","DOI":"10.1177\/074873049601100305","type":"journal-article","created":{"date-parts":[[2007,3,11]],"date-time":"2007-03-11T03:24:21Z","timestamp":1173583461000},"page":"234-240","source":"Crossref","is-referenced-by-count":13,"title":["Light-Induced Phase Shifting of the Circadian Conidiation Rhythm Is Inhibited by Calmodulin Antagonists in Neurospora crassa"],"prefix":"10.1177","volume":"11","author":[{"given":"Yutaka","family":"Sadakane","sequence":"first","affiliation":[{"name":"Department of Biology, Faculty of Science, Okayama University, Tsushimanaka 3-1, Okayama 700, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Science, Okayama University, Tsushimanaka 3-1, Okayama 700, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1177\/074873049400900102"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(05)80005-4"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1104\/pp.63.6.1049"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1995.tb03963.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.61.070192.003015"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.7.4354"},{"key":"atypb7","doi-asserted-by":"crossref","unstructured":"Hidaka H. and Kobayashi R. (1993) Use of protein (serine\/ threonine) kinase activators and inhibitors to study protein phosphorylation in intact cells. In Protein Phosphorylation : A Practical Approach, DG Hardie, ed, pp 87-107, Oxford University Press, New York.","DOI":"10.1093\/oso\/9780199633067.003.0004"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1177\/074873049000500207"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00603950"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.49.070180.002421"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90124-H"},{"key":"atypb13","first-page":"231","volume":"22","author":"Nakashima H.","year":"1981","journal-title":"Plant Cell Physiol"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1177\/074873048600100207"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90272-R"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.58.4.1762"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511600401.013"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-171403-1.50009-6"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.pcp.a078782"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)47638-7"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1104\/pp.42.11.1504"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1016\/0955-0674(93)90111-3"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1126\/science.1646483"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1177\/074873049400900103"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1104\/pp.99.4.1416"},{"key":"atypb26","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1242\/jcs.104.3.861","volume":"104","author":"Szollosi MS","year":"1993","journal-title":"J Cell Sci"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691715"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(86)80500-9"},{"key":"atypb29","first-page":"42","volume":"13","author":"Vogel HJ","year":"1956","journal-title":"Microbial Genetic Bulletin"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1104\/pp.100.3.1369"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1126\/science.256.5055.370"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-171401-7.50021-5"}],"container-title":["Journal of Biological Rhythms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/074873049601100305","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/074873049601100305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:01:27Z","timestamp":1777492887000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/074873049601100305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,9]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,9]]}},"alternative-id":["10.1177\/074873049601100305"],"URL":"https:\/\/doi.org\/10.1177\/074873049601100305","relation":{},"ISSN":["0748-7304","1552-4531"],"issn-type":[{"value":"0748-7304","type":"print"},{"value":"1552-4531","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,9]]}}}