{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T10:24:33Z","timestamp":1789035873332,"version":"build-2803163510"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,7,16]],"date-time":"2023-07-16T00:00:00Z","timestamp":1689465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Palliat Care"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>A 65-year-old female patient could no longer take oral food or medications due to a duodenal occlusion associated with metastatic urothelial carcinoma. Her pre-existing chemotherapy-induced polyneuropathy had been well treated with pregabalin orally.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Since only preparations for oral use of pregabalin are available, pregabalin suppositories were compounded by the hospital pharmacy for rectal use in this patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>With the rectal administration, the treatment was successfully continued; we measured a good increase in serum levels and the symptoms improved significantly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Cancer patients often need to be treated with co-analgesics. At the end of life, treatment often cannot be continued due to lack of other than oral administration. Our case adds to the low evidence of pregabalin administered rectally.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08258597231189151","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:24:10Z","timestamp":1689553450000},"page":"412-415","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Successful use of Rectal Pregabalin for the Treatment of Chemotherapy-Induced Neuropathic Pain\u2014a Case Report"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5891-5842","authenticated-orcid":false,"given":"Carmen","family":"Roch","sequence":"first","affiliation":[{"name":"Interdisciplinary Center for Palliative Medicine, University Hospital Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Servet","family":"Para","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center for Palliative Medicine, University Hospital Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Brandhofer","sequence":"additional","affiliation":[{"name":"Pharmacy of the University Hospital Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna K.","family":"Seitz","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology, University Hospital Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7655-0306","authenticated-orcid":false,"given":"Constanze","family":"R\u00e9mi","sequence":"additional","affiliation":[{"name":"Pharmacy University Hospital of Munich, Munich, Germany"},{"name":"Department for Palliative Medicine, University Hospital of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Berner","sequence":"additional","affiliation":[{"name":"Pharmacy University Hospital of Munich, Munich, Germany"},{"name":"Department for Palliative Medicine, University Hospital of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitt","family":"van Oorschot","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center for Palliative Medicine, University Hospital Wuerzburg, Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,7,16]]},"reference":[{"key":"bibr1-08258597231189151","doi-asserted-by":"publisher","DOI":"10.1185\/030079906X132488"},{"key":"bibr2-08258597231189151","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.13051"},{"key":"bibr3-08258597231189151","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-211511"},{"key":"bibr4-08258597231189151","unstructured":"DAC-Anlage F Verdr\u00e4ngungsfaktoren f\u00fcr Z\u00e4pfchen und Vaginalz\u00e4pfchen Stand DAC 2019-2 [Internet]. 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