{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T09:55:23Z","timestamp":1777802123695,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:p>Seizures are commonly associated with hypoxic-ischemic encephalopathy. Although the majority of cases are controlled with first- or second-line therapy, others develop pervasive seizures, requiring multiple anticonvulsants. To provide data on the incidence of seizures and response to anticonvulsant therapies, a cohort of 90 term infants with hypoxic-ischemic encephalopathy treated at our institution between January 1, 1995, and July 1, 1999, was reviewed. Of the 60 infants who developed seizures, 59 received phenobarbital initially; in 29 cases, the seizures resolved. The remaining 30 infants received phenytoin as a second-line anticonvulsant, and seizures stopped in 10 cases. The 20 infants with ongoing pervasive seizures were treated with intravenous paraldehyde. (J Child Neurol 2001;16:915-917).<\/jats:p>","DOI":"10.1177\/088307380101601210","type":"journal-article","created":{"date-parts":[[2008,3,31]],"date-time":"2008-03-31T18:40:10Z","timestamp":1206988810000},"page":"915-917","source":"Crossref","is-referenced-by-count":9,"title":["Pervasive Seizures Caused by Hypoxic-Ischemic Encephalopathy: Treatment With Intravenous Paraldehyde"],"prefix":"10.1177","volume":"16","author":[{"given":"Damien L.","family":"Armstrong","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Newborn Services, National Women's Hospital and The University of Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcolm R.","family":"Battin","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Newborn Services, National Women's Hospital and The University of Auckland, New Zealand,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,12,1]]},"reference":[{"key":"atypb1","first-page":"83","volume":"156","author":"Rennie J.","year":"1997","journal-title":"J Paediatr"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908123410704"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-198806000-00006"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)81017-3"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.1.108"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1136\/fn.78.1.F70"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(96)90001-7"},{"key":"atypb8","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1542\/peds.70.2.165","volume":"70","author":"Holden KR","year":"1982","journal-title":"Pediatrics"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1378\/chest.82.3.371"},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1542\/peds.57.1.158","volume":"57","author":"Sinai SH","year":"1976","journal-title":"Pediatrics"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199631060-00003"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1007\/BF00637740"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1988.tb03757.x"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.59.698.801"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(69)90026-X"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/088307380101601210","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/088307380101601210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:31:57Z","timestamp":1777494717000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/088307380101601210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1177\/088307380101601210"],"URL":"https:\/\/doi.org\/10.1177\/088307380101601210","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}