{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:32:42Z","timestamp":1790260362591,"version":"4.1.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2003,11,1]],"date-time":"2003-11-01T00:00:00Z","timestamp":1067644800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:p>A prospective study of Guillain-Barr\u00e9 syndrome from January 1992 to December 2001 was undertaken. Intravenous immunoglobulins were used in all patients. All patients were followed up until complete recovery. Various parameters, such as onset of weakness, duration of hospital stay, ventilation requirement, residual deficit, and mortality, were recorded. Acute relapses and fluctuations were also noted. The pattern of this group was compared with patients before 1992, who were not given intravenous immunoglobulins in the Sultanate of Oman. Our data were compared with a few studies prior to 1992 from the medical literature. Our study revealed a definite benefit with intravenous immunoglobulins. The disease course and hospital stay were shortened. Fewer patients needed ventilation. There was no mortality, and the residual deficit was less than 5%. Occasional relapses at a later stage in the course of illness have been noted in acute Guillain-Barr\u00e9 syndrome. However, acute relapse, a new phenomenon that was not seen in the pre\u2014intravenous immunoglobulin era, stood at 11.9%. Intravenous immunoglobulins have made a significant difference in the outcome of Guillain-Barr\u00e9 syndrome, but one has to be aware of acute relapses, which usually occur in the first 2 to 3 weeks after administration. ( J Child Neurol 2003;18:767\u2014771).<\/jats:p>","DOI":"10.1177\/08830738030180110501","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T22:00:05Z","timestamp":1182463205000},"page":"767-771","source":"Crossref","is-referenced-by-count":18,"title":["Ten-Year Prospective Study (Clinical Spectrum) of Childhood Guillain-Barr\u00e9 Syndrome in the Arabian Peninsula: Comparison of Outcome in Patients in the Pre\u2014 and Post\u2014Intravenous Immunoglobulin Eras"],"prefix":"10.1177","volume":"18","author":[{"given":"Roshan","family":"Koul","sequence":"first","affiliation":[{"name":"Department of Child Health, Sultan Qaboos University Hospital, Al Khod, Sultanate of Oman, , ."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Chacko","sequence":"additional","affiliation":[{"name":"Department of Child Health, Sultan Qaboos University Hospital, Al Khod, Sultanate of 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