{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:56:30Z","timestamp":1790747790296,"version":"4.1.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:p>This study investigated treatment patterns at discharge in infants with neonatal seizures and evaluated the impact of outpatient phenobarbital prophylaxis on the frequency of seizure recurrence and the long-term neurodevelopmental outcome at 1 to 11 years. Infants with neonatal seizures during a 12-year period were identified retrospectively (n = 146), and data were obtained by medical chart review. Outcomes were ascertained by standardized telephone survey. Thirty-three infants (23%) were taking phenobarbital, and 99 infants (68%) were taking no anticonvulsants at discharge. Comparisons were made between these 2 groups. Phenobarbital prophylaxis did not improve neurologic outcomes, either with respect to seizure recurrence or neurologic development. These data have important implications at a time when many are questioning the practice of prophylaxis after neonatal seizures and when newer anticonvulsants are being recommended for treatment of acute neonatal seizures.<\/jats:p>","DOI":"10.1177\/0883073807301917","type":"journal-article","created":{"date-parts":[[2007,6,11]],"date-time":"2007-06-11T11:48:38Z","timestamp":1181562518000},"page":"389-395","source":"Crossref","is-referenced-by-count":59,"title":["Seizure Recurrence and Developmental Disabilities After Neonatal Seizures: Outcomes Are Unrelated to Use of Phenobarbital Prophylaxis"],"prefix":"10.1177","volume":"22","author":[{"given":"Ronnie","family":"Guillet","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Golisano Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Kwon","sequence":"additional","affiliation":[{"name":"Departments of Neurology and Pediatrics, University of 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