{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:07:50Z","timestamp":1777802870609,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p>We report the exercise capacity of an 8-year-old boy with clinical, histological, biochemical, and genetic evidence of McArdle disease. The patient presented with severe myalgia, proteinuria, hematuria, pyrexia, and elevated creatine kinase after swimming. After pre-exercise ingestion of sucrose, he performed treadmill exercise to symptom limitation. His peak oxygen uptake (18.8 mL\/kg\/min) and ventilatory threshold (16.0 mL\/kg\/min) were reduced by 40% and 20% compared with healthy age-matched and gender-matched controls. The results suggest that exercise capacity is reduced early in life in patients with McArdle disease and suggest the need for prophylactic exercise training (following pre-exercise feeding to prevent rhabdomyolysis) to minimize deconditioning.<\/jats:p>","DOI":"10.1177\/0883073807304206","type":"journal-article","created":{"date-parts":[[2007,8,22]],"date-time":"2007-08-22T11:38:05Z","timestamp":1187782685000},"page":"880-882","source":"Crossref","is-referenced-by-count":14,"title":["Exercise Capacity in a Child With McArdle Disease"],"prefix":"10.1177","volume":"22","author":[{"given":"Margarita","family":"P\u00e9rez","sequence":"first","affiliation":[{"name":"Universidad Europea de Madrid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 L.","family":"Mat\u00e9-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Universidad Europea de Madrid"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Foster","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science, University of Wisconsin-La Crosse"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan C.","family":"Rubio","sequence":"additional","affiliation":[{"name":"Hospital Universitario 12 de Octubre, Madrid, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoni L.","family":"Andreu","sequence":"additional","affiliation":[{"name":"Centre d'Investigacions en Bioqu\u00edmica y Biolog\u00eda Molecular, Hospital Universitari Vall d'Hebron, Barcelona, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel A.","family":"Mart\u00edn","sequence":"additional","affiliation":[{"name":"Hospital Universitario 12 de Octubre, Madrid, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaqu\u00edn","family":"Arenas","sequence":"additional","affiliation":[{"name":"Hospital Universitario 12 de Octubre, Madrid, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Lucia","sequence":"additional","affiliation":[{"name":"Universidad Europea de Madrid,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199307223290404"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2006.030791"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20645"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20881"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031836"},{"key":"atypb6","first-page":"154","volume":"32","author":"Colomer Oferil J","year":"1990","journal-title":"An Esp Pediatr"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)83287-1"},{"key":"atypb8","first-page":"136","volume":"18","author":"L\u00f3pez Mart\u00edn A.","year":"2001","journal-title":"An Med Interna."},{"issue":"1","key":"atypb9","doi-asserted-by":"crossref","DOI":"10.1055\/s-2006-924037","volume":"38","author":"Meyer T.","year":"2005","journal-title":"Int J Sports Med"},{"key":"atypb10","unstructured":"McArdle WD, Katch FI, Katch VL Exercise Physiology. Energy, Nutrition and Performance. 5th ed. Philadelphia, Penn: Lippincott Williams & Wilkins; 2001:183."},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00024.2003"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011858"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073807304206","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073807304206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:34:15Z","timestamp":1777494855000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073807304206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1177\/0883073807304206"],"URL":"https:\/\/doi.org\/10.1177\/0883073807304206","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}