{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:13:40Z","timestamp":1777803220781,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:p>Few cases of simultaneous acute demyelination of the peripheral and central nervous systems are reported. Four patients diagnosed as having Guillain-Barr\u00e9 syndrome and acute disseminated encephalomyelitis during the same hospitalization are described herein. Two patients manifest an atypical form of Guillain-Barr\u00e9 syndrome, with magnetic resonance imaging of the head showing acute disseminated encephalomyelitis. A third patient has acute disseminated encephalomyelitis and develops Guillain-Barr\u00e9 syndrome during his hospitalization. A fourth patient demonstrates transverse myelitis that evolves into Guillain-Barr\u00e9 syndrome, with demyelination seen on brain magnetic resonance imaging. All patients are treated with intravenous immunoglobulins or corticosteroids. Three patients have a favorable outcome; 1 patient has a chronic inflammatory demyelinating polyradiculoneuropathy. Guillain-Barr\u00e9 syndrome and acute disseminated encephalomyelitis can occur simultaneously in the pediatric population. This may be explained by a shared epitope between peripheral and central nervous system myelin. Further research is necessary to better describe this entity and its prognosis.<\/jats:p>","DOI":"10.1177\/0883073808314360","type":"journal-article","created":{"date-parts":[[2008,3,19]],"date-time":"2008-03-19T21:56:07Z","timestamp":1205963767000},"page":"752-757","source":"Crossref","is-referenced-by-count":24,"title":["Simultaneous Guillain-Barr\u00e9 Syndrome and Acute Disseminated Encephalomyelitis in the Pediatric Population"],"prefix":"10.1177","volume":"23","author":[{"given":"Genevi\u00e8ve","family":"Bernard","sequence":"first","affiliation":[{"name":"Division of Neurology and Neurosurgery, Montreal Children's Hospital, McGill University, Quebec, Canada,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9milie","family":"Riou","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurosurgery, Montreal Children's Hospital, McGill University, Quebec, 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