{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:55:19Z","timestamp":1789829719862,"version":"4.0.1"},"reference-count":42,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2009,1,30]],"date-time":"2009-01-30T00:00:00Z","timestamp":1233273600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:p>We examined the rates of comorbid pervasive developmental disorders in participants with Tourette syndrome. We used 7288 participants from the Tourette Syndrome International Database Consortium Registry. We found 334 (4.6%; 1 of every 22 participants) with Tourette syndrome had a comorbid pervasive developmental disorder. In participants with Tourette syndrome and comorbid pervasive developmental disorders, 98.8% had one or more comorbidities (pervasive developmental disorder was not counted) compared to 13.2% in the group of participants with Tourette syndrome only. Variables from logistic modeling that were significant predictors of Tourette syndrome and pervasive developmental disorders were: male gender; no family history of tics\/Tourette syndrome; and an increased number of comorbidities (P &lt; .001). We found rates of comorbid Tourette syndrome and pervasive developmental disorders to be increased by 13 times. Identification of differences between subgroups of patients with Tourette syndrome may increase understanding of syndromal susceptibility, severity, and outcome.<\/jats:p>","DOI":"10.1177\/0883073808322666","type":"journal-article","created":{"date-parts":[[2009,1,30]],"date-time":"2009-01-30T16:58:48Z","timestamp":1233334728000},"page":"170-175","source":"Crossref","is-referenced-by-count":72,"title":["Tourette Syndrome and Comorbid Pervasive Developmental Disorders"],"prefix":"10.1177","volume":"24","author":[{"given":"Larry","family":"Burd","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Kerbeshian","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn G.","family":"Klug","sequence":"additional","affiliation":[{"name":"Center for Rural Health, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger D.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Neuropsychiatry Clinic, BC Children's Hospital, and University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,1,30]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70313-3"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1177\/088307380101600609"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.1.14"},{"key":"atypb4","volume-title":"Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR 4th Ed. Text Revision","author":"American Psychiatric Association.","year":"2000"},{"key":"atypb5","first-page":"67","volume":"58","author":"Kerbeshian J.","year":"1992","journal-title":"Adv Neurol."},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162200000839"},{"key":"atypb7","volume-title":"Tourette Syndrome and Human Behavior","author":"Comings DE","year":"1990"},{"key":"atypb8","volume-title":"Diagnostic and Statistical Manual of Mental Disorders DSM-IV","author":"American Psychiatric Association.","year":"1994","edition":"4"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1990.tb02275.x"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-198709000-00014"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1007\/BF02211943"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1988.tb00735.x"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1007\/BF01495061"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01239-8"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200006000-00007"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.24.3093"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200107000-00017"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.5.1155"},{"key":"atypb19","unstructured":"California State Department of Developmental Services. Changes in the population of persons with autism and pervasive developmental disorders in California's Developmental Services System: 1987 through 1998. A report to the legislature: March 1, 1999. Sacramento, CA: California Health and Human Services Agency; 1999."},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200106000-00005"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291704002387"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2005.tb01034.x"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206001964"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1177\/1362361302006002002"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1177\/1362361307086663"},{"key":"atypb26","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fml091"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-003-0325-3"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1007\/s007870200003"},{"key":"atypb29","first-page":"226","volume":"38","author":"Cohen DJ","year":"2001","journal-title":"Isr J Psychiatry Relat Sci"},{"key":"atypb30","first-page":"89","volume":"85","author":"Rapin I.","year":"2001","journal-title":"Adv Neurol"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005608014889"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(20000207)96:1<69::AID-AJMG14>3.0.CO;2-5"},{"key":"atypb33","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199605000-00024"},{"key":"atypb34","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320540316"},{"key":"atypb35","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70317-0"},{"key":"atypb36","doi-asserted-by":"publisher","DOI":"10.3109\/00048679309075829"},{"key":"atypb37","doi-asserted-by":"publisher","DOI":"10.3109\/10401239309148976"},{"key":"atypb38","doi-asserted-by":"publisher","DOI":"10.1007\/BF01046229"},{"key":"atypb39","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320390213"},{"key":"atypb40","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00434"},{"key":"atypb41","doi-asserted-by":"publisher","DOI":"10.1017\/S003329179900896X"},{"key":"atypb42","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.3.522"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073808322666","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073808322666","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:33:36Z","timestamp":1777494816000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073808322666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,30]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["10.1177\/0883073808322666"],"URL":"https:\/\/doi.org\/10.1177\/0883073808322666","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1158026.618111","asserted-by":"object"}]},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,30]]}}}