{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:20:14Z","timestamp":1778552414103,"version":"3.51.4"},"reference-count":54,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T00:00:00Z","timestamp":1236124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:p>We report a child presenting with severe demyelinating myelitis complicated with critical illness polyneuropathy. This previously healthy 8-month-old boy presented with acute superior limb weakness, absent tendon reflexes, and respiratory failure. Spinal magnetic resonance imaging showed an extensive cervical demyelinating lesion. Spinal cord trauma was suspected and high doses of dexamethasone were administered. Electromyography and nerve conduction studies showed absence of compound muscle action potentials and sural nerve sensory action potential, which was suggestive of a severe Guillain-Barr\u00e9 syndrome. However, intravenous immunoglobulins did not induce any improvement. Afterward, sural nerve biopsy showed a mild neuropathy, but muscle biopsy revealed abnormalities compatible with severe critical illness myopathy. After 5 months of evolution without improvement, the patient died following withdrawal of life support therapy. This case highlights the possible occurrence of critical illness polyneuromyopathy when treatment with corticosteroids are used in patients with acute demyelinating myelitis.<\/jats:p>","DOI":"10.1177\/0883073808330166","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T23:37:22Z","timestamp":1236296242000},"page":"758-762","source":"Crossref","is-referenced-by-count":3,"title":["Critical Illness Polyneuromyopathy in a Child with Severe Demyelinating Myelitis"],"prefix":"10.1177","volume":"24","author":[{"given":"Tanja","family":"Adamovic","sequence":"first","affiliation":[{"name":"Division of Pediatric Critical Care, Department of Pediatrics, CHU Sainte-Justine, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariane","family":"Willems","sequence":"additional","affiliation":[{"name":"Division of Pediatric Critical Care, Department of Pediatrics, CHU Sainte-Justine, 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