{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:56:03Z","timestamp":1788580563026,"version":"build-2803163510"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:p>The authors conducted this study to identify whether bacille Calmette-Gu\u00e9rin (BCG) vaccination leads to an altered spectrum of neuroimaging findings outcome in pediatric patients with tuberculous meningitis. This retrospective study was conducted through chart review and review of computed tomography (CT) scans and magnetic resonance imaging (MRI) of patients with confirmed central nervous system tuberculosis from the year 1992 to 2005, at a large tertiary care hospital in Karachi, Pakistan. A total of 108 pediatric patients with tuberculous meningitis were included in the analysis. Of the 108 patients, 63 (58.3%) were male and 45 (41.7%) had received bacille Calmette-Gu\u00e9rin vaccination. There was no difference in terms of severity of clinical presentation and outcome between vaccinated and unvaccinated group. There were no significant differences in CT or MRI findings between the 2 groups except for tuberculomas on MRI, which were significantly higher in the non\u2014bacille Calmette-Gu\u00e9rin vaccinated group (52.2% vs 22.7%, P = .042). Bacille Calmette-Gu\u00e9rin vaccination appears to translate into less tuberculoma formation on MRI.<\/jats:p>","DOI":"10.1177\/0883073809340921","type":"journal-article","created":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T22:25:55Z","timestamp":1254349555000},"page":"581-586","source":"Crossref","is-referenced-by-count":9,"title":["Impact of Bacille Calmette-Gu\u00e9rin Vaccination on Neuroradiological Manifestations of Pediatric Tuberculous Meningitis"],"prefix":"10.1177","volume":"25","author":[{"given":"Mohammad","family":"Wasay","sequence":"first","affiliation":[{"name":"Department of Neurology, The Aga Khan University, Karachi, Pakistan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Ajmal","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ather M.","family":"Taqui","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najam","family":"Uddin","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iqbal","family":"Azam","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, The Aga Khan University, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousuf","family":"Husen","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Aga Khan University, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Qamaruddin","family":"Nizami","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,9,30]]},"reference":[{"key":"atypb1","volume-title":"Global tuberculosis control 2008","author":"World Health Organization.","year":"2008"},{"key":"atypb2","volume-title":"World population data sheet 2008","author":"Population Reference Bureau.","year":"2008"},{"key":"atypb3","volume-title":"Infections of the Central Nervous System","author":"Scheld WM","year":"2004"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70019-3"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.5.e49"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/17.6.987"},{"key":"atypb7","volume-title":"Overview of Clinical Tuberculosis. Tuberculosis: Pathogenesis, Protection, and Control","author":"Hopewell PC","year":"1994"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00772-2"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(20)30376-7"},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1542\/peds.28.4.622","volume":"28","author":"Rosenthal SR","year":"1961","journal-title":"Pediatrics"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6082.293"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.64.3.283"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/22.6.1154"},{"issue":"1","key":"atypb14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1542\/peds.96.1.29","volume":"96","author":"Colditz GA","year":"1995","journal-title":"Pediatrics"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.065201"},{"issue":"11","key":"atypb16","first-page":"885","volume":"2","author":"Guler N.","year":"1998","journal-title":"Int J Tuberc Lung Dis"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01534.x"},{"key":"atypb18","first-page":"83","volume":"54","author":"Wasay M.","year":"2004","journal-title":"J Pak Med Assoc"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1007\/BF02021522"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2003.tb00185.x"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073809340921","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073809340921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:35:10Z","timestamp":1777494910000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073809340921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,30]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["10.1177\/0883073809340921"],"URL":"https:\/\/doi.org\/10.1177\/0883073809340921","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,30]]}}}