{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T05:42:23Z","timestamp":1777959743913,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2010,6,2]],"date-time":"2010-06-02T00:00:00Z","timestamp":1275436800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:p>Blindness is an uncommon but devastating complication of tuberculosis meningitis. The main causes are chronically raised intracranial pressure (hydrocephalus and\/or tuberculomas) or direct involvement of the optic chiasm or optic nerves by the basal arachnoiditis (inflammation and\/or compression). Antituberculosis therapy combined with corticosteroids and control of intracranial pressure constitutes the mainstay of therapy for tuberculous meningitis. Despite these treatment measures, some patients develop blindness, mainly as a result of progressive optochiasmatic arachnoiditis. This led us to explore the role of adjuvant thalidomide therapy, and we describe the dramatic recovery of vision in 4 consecutive cases. Clinical recovery was accompanied by marked radiological improvement on magnetic resonance imaging (MRI) of the brain.<\/jats:p>","DOI":"10.1177\/0883073809350507","type":"journal-article","created":{"date-parts":[[2010,6,2]],"date-time":"2010-06-02T22:59:25Z","timestamp":1275519565000},"page":"822-828","source":"Crossref","is-referenced-by-count":47,"title":["Tuberculous Meningitis-Related Optic Neuritis: Recovery of Vision With Thalidomide in 4 Consecutive Cases"],"prefix":"10.1177","volume":"25","author":[{"given":"Johan F.","family":"Schoeman","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Child Health, Tygerberg Children's Hospital, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Savvas","family":"Andronikou","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tygerberg Hospital, Faculty of Health Sciences, University of Stellenbosch, Western Cape, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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