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The most common presenting symptoms were paresthesias (54%), weakness (49%), and myalgias (49%). Sensation was affected in 54% of patients, and hyporeflexia or areflexia was present in 94% of patients. Cranial nerve dysfunction (46%) and autonomic involvement (eg, changes in blood pressure, pulse, bowel\/bladder control, or priapism; 46%) were also common. Autonomic dysfunction, cranial nerve involvement, and albuminocytological dissociation were significantly associated with a decreased time to nadir, the point when symptoms peaked (P = .015, .007, and .005, respectively). Although not statistically significant, treatment with plasmapheresis had a better success rate than intravenous immunoglobulin. The authors\u2019 results will help to further delineate the clinical picture of Guillain-Barr\u00e9 syndrome in children and refine treatment strategies.<\/jats:p>","DOI":"10.1177\/0883073810370481","type":"journal-article","created":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T20:19:01Z","timestamp":1283890741000},"page":"1504-1510","source":"Crossref","is-referenced-by-count":31,"title":["A Clinical Picture of Guillain-Barr\u00e9 Syndrome in Children in the United States"],"prefix":"10.1177","volume":"25","author":[{"given":"Caitlin W.","family":"Hicks","sequence":"first","affiliation":[{"name":"Cleveland Clinic, Cleveland, OH, Cleveland Clinic Lerner College of Medicine, Cleveland, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Kay","sequence":"additional","affiliation":[{"name":"University of Cincinnati College of Medicine, Cincinnati, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Worley","sequence":"additional","affiliation":[{"name":"Cleveland Clinic, Cleveland, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manikum","family":"Moodley","sequence":"additional","affiliation":[{"name":"Cleveland Clinic, Cleveland, OH,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9,7]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000081231.08914.A1"},{"key":"atypb2","first-page":"191","volume":"19","author":"Sladky JT","year":"2004","journal-title":"J Child Neurol"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200464060-00003"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2008.01325.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1177\/088307380001500308"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000265396.87983.bd"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1136\/adc.74.4.281"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199204233261706"},{"key":"atypb9","doi-asserted-by":"crossref","unstructured":"Winer JB Guillain-Barre syndrome. 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