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Individuals with neurofibromatosis type 1 are also at increased risk to develop moyamoya syndrome, which is a cerebrovascular condition that predisposes affected individuals to develop strokes as a result of progressive narrowing of the intracranial internal carotid arteries and failure of adequate blood supply through collateral vessels. We report a case of a young boy with neurofibromatosis type 1 with glioblastoma who developed rapidly progressive moyamoya vasculopathy after treatment with the angiogenesis inhibitor bevacizumab.<\/jats:p>","DOI":"10.1177\/0883073810379639","type":"journal-article","created":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T20:19:01Z","timestamp":1283890741000},"page":"228-230","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Association of Rapidly Progressive Moyamoya Syndrome With Bevacizumab Treatment for Glioblastoma in a Child With Neurofibromatosis Type 1"],"prefix":"10.1177","volume":"26","author":[{"given":"Nicole J.","family":"Ullrich","sequence":"first","affiliation":[{"name":"Department of Neurology, Children's Hospital Boston, Boston, Massachusetts, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MaryAnn","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, Department of Hematology\/Oncology, Children's Hospital Boston, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Children's Hospital Boston, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mira","family":"Irons","sequence":"additional","affiliation":[{"name":"Department of Genetics, Children's Hospital Boston, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Marcus","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Children's Hospital Boston, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark W.","family":"Kieran","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, Department of Hematology\/Oncology, Children's Hospital Boston, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9,7]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990326)89:1<1::AID-AJMG3>3.0.CO;2-8"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804622"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000150544.00016.69"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0152"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000257095.33125.48"},{"key":"atypb6","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/pbc.22462","volume":"54","author":"Huttner AJ","year":"2010","journal-title":"Pediatr Blood Cancer"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.10260"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.12.2160"},{"key":"atypb9","first-page":"544","volume":"50","author":"Soriano SG","year":"2002","journal-title":"Neurosurgery"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.2174\/156720206778018730"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.12.2440"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073810379639","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073810379639","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:36:08Z","timestamp":1777494968000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073810379639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,7]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["10.1177\/0883073810379639"],"URL":"https:\/\/doi.org\/10.1177\/0883073810379639","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,7]]}}}