{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:17:06Z","timestamp":1777803426038,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,10,6]],"date-time":"2010-10-06T00:00:00Z","timestamp":1286323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:p>Risperidone is widely used in children with autism spectrum disorders for behavioral modification. In this study, the authors aimed to (1) describe a clinic-referred sample of patients with an autism spectrum disorder on risperidone, (2) identify differences between the success and nonsuccess groups, and (3) describe our experience with young children (&lt; age 5 years) on risperidone. Eighty patients were initiated on risperidone. Indications included aggression (66%), impulsivity (14%), and stereotypies (4%). Sixty-six percent met criteria for success at 6 months and 53% at 1 year. Sixty-seven percent of the nonsuccess group reported side effects, compared to 47% of the success group. Weight gain was the most common side effect in both groups, followed by somnolence. Somnolence was the most robust predictor of nonsuccess. In our clinic-referred sample, the short-term success rate of risperidone was more than 50%, and side effects limited its use. Although weight gain was common, somnolence more significantly influenced treatment discontinuation.<\/jats:p>","DOI":"10.1177\/0883073810382143","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T20:15:46Z","timestamp":1286482546000},"page":"428-432","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":33,"title":["Risperidone Use in Autism Spectrum Disorders: A Retrospective Review of a Clinic-Referred Patient Population"],"prefix":"10.1177","volume":"26","author":[{"given":"Monica E.","family":"Lemmon","sequence":"first","affiliation":[{"name":"Harvard Medical School, Boston, MA, USA, The Johns Hopkins Hospital, Department of Pediatrics, Baltimore, MD, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matt","family":"Gregas","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston, MA, USA, Children's Hospital Boston, Clinical Research Department, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shafali S.","family":"Jeste","sequence":"additional","affiliation":[{"name":"UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,10,6]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073807307102"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2008.01065.x"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1352\/0895-8017(2007)112[439:LOIFPP]2.0.CO;2"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1080\/hrp_8.2.45"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199706000-00022"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(94)90174-0"},{"key":"atypb7","first-page":"155","volume":"33","author":"Findling RL","year":"1997","journal-title":"Psychopharmacol Bull"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199705000-00020"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199804000-00014"},{"key":"atypb10","first-page":"79","volume":"10","author":"Zuddas A.","year":"2000","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2003-0264-F"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013171"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2009.0022"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1097\/01.chi.0000177055.11229.76"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(01)00264-0"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852900008348"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073810382143","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073810382143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:36:16Z","timestamp":1777494976000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073810382143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,6]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1177\/0883073810382143"],"URL":"https:\/\/doi.org\/10.1177\/0883073810382143","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,6]]}}}