{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:18:16Z","timestamp":1777803496120,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2011,4,4]],"date-time":"2011-04-04T00:00:00Z","timestamp":1301875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>Occurrence of hypsarrhythmia after the age of 3 years is rare. The objective of this study is to describe a group of patients who have persistence of hypsarrhythmia after the age of 3 years. The authors retrospectively reviewed the EEGs of 24 patients with hypsarrhythmia. Electroencephalographies (EEGs) were scored using a hypsarrhythmia scale. The clinical data of 7 patients with EEG scores greater than 9 at ages \u22653 years were analyzed. The mean age was 5.7 years (range, 3-8.7 years). EEG background amplitudes ranged from 200 to 500 \u00b5V in 5 patients and it was greater than 500 \u00b5V in the other 2. Six patients had electrodecremental responses. The etiology was developmental in 3 patients, mitochondrial disease in 2, and hypoxic ischemic encephalopathy in 2. Our study suggests that a subgroup of patients with hypsarrhythmia may not transition to a Lennox-Gastaut pattern or normalization after the age of 3 years.<\/jats:p>","DOI":"10.1177\/0883073810394849","type":"journal-article","created":{"date-parts":[[2011,4,4]],"date-time":"2011-04-04T23:15:36Z","timestamp":1301958936000},"page":"835-837","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Persistence of Hypsarrhythmia in Children Beyond the Age of Three Years"],"prefix":"10.1177","volume":"26","author":[{"given":"Kandan","family":"Kulandaivel","sequence":"first","affiliation":[{"name":"Department of Neurology, Hahnemann University Hospital, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya S.","family":"Khurana","sequence":"additional","affiliation":[{"name":"Section of Neurology, Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen S.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Section of Neurology, Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph J.","family":"Melvin","sequence":"additional","affiliation":[{"name":"Section of Neurology, Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agustin","family":"Legido","sequence":"additional","affiliation":[{"name":"Section of Neurology, Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Valencia","sequence":"additional","affiliation":[{"name":"Section of Neurology, Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,4,4]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1542\/peds.13.1.66","volume":"13","author":"Gibbs EL","year":"1954","journal-title":"Pediatrics"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(00)00238-1"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1987.tb00010.x"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(87)80110-9"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1177\/155005949502600105"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1973.tb05169.x"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2002.28401.x"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1973.tb03952.x"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1970.tb01934.x"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.1.197"},{"key":"atypb11","first-page":"321","volume":"35","author":"Yamatogi Y.","year":"1981","journal-title":"Folia Psychiatr Neurol Jpn"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073810394849","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073810394849","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:36:33Z","timestamp":1777494993000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073810394849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,4]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1177\/0883073810394849"],"URL":"https:\/\/doi.org\/10.1177\/0883073810394849","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,4]]}}}