{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T14:49:30Z","timestamp":1793803770296,"version":"4.6.1"},"reference-count":8,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T00:00:00Z","timestamp":1348444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:p>\n                    The few cases of antiphospholipid syndrome that have been reported in neonates are believed to have resulted from a transplacental transfer of antiphospholipid antibodies. Here we report on a boy with a neonatal stroke revealing a de novo primary antiphospholipid, the mother being free of antiphospholipid antibodies. Other thrombosis risk factors included primiparity, gestational diabetes, macrosomia, polyglobulia, and lipoprotein(a) &gt;30 mg\/dL. Anti-cardiolipin and anti-\u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -glycoprotein I persisted more than 2 years. Under aspirin therapy, the child did not exhibit recurrence of thrombotic events or symptoms of autoimmunity after a follow-up of 3 years. Our case indicates that clinicians should consider a second retesting for anticardiolipin antibodies and anti-\u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -glycoprotein I antibodies, even when children and mother neonatal tests are negative.\n                  <\/jats:p>","DOI":"10.1177\/0883073811435238","type":"journal-article","created":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T06:13:55Z","timestamp":1348467235000},"page":"1340-1342","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["A Case of Infantile De Novo Primary Antiphospholipid Syndrome Revealed by a Neonatal Arterial Ischemic Stroke"],"prefix":"10.1177","volume":"27","author":[{"given":"Etienne","family":"Merlin","sequence":"first","affiliation":[{"name":"CHU Clermont-Ferrand, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Dor\u00e9","sequence":"additional","affiliation":[{"name":"CHU Clermont-Ferrand, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Chabrier","sequence":"additional","affiliation":[{"name":"Groupe de recherche sur la Thrombose, Saint-\u00c9tienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Biard","sequence":"additional","affiliation":[{"name":"CHU Clermont-Ferrand, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Marques-Verdier","sequence":"additional","affiliation":[{"name":"CHU Clermont-Ferrand, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"St\u00e9phan","sequence":"additional","affiliation":[{"name":"CHU Saint-Etienne, Unit\u00e9 d\u2019h\u00e9matologie et oncologie, H\u00f4pital Nord, Saint-\u00c9tienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,9,24]]},"reference":[{"key":"bibr1-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1177\/0961203310375263"},{"key":"bibr2-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2010.10.003"},{"key":"bibr3-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1209"},{"key":"bibr4-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1177\/0961203307079039"},{"key":"bibr5-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.913673"},{"key":"bibr6-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.527283"},{"key":"bibr7-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000103745.03393.39"},{"key":"bibr8-0883073811435238","doi-asserted-by":"publisher","DOI":"10.1002\/art.22360"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073811435238","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0883073811435238","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073811435238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:36:54Z","timestamp":1777495014000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073811435238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,24]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1177\/0883073811435238"],"URL":"https:\/\/doi.org\/10.1177\/0883073811435238","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,24]]}}}