{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:20:00Z","timestamp":1777803600950,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T00:00:00Z","timestamp":1330387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>Niemann-Pick disease type C, an autosomal recessive lysosomal storage disorder, can present with severe visceral and neurologic involvement and is associated with a significant decrease in life expectancy. As little is known about anesthetic considerations of this disease, we examined the perianesthetic course of patients with Niemann-Pick disease type C. Thirty-two patients with Niemann-Pick disease type C, median age 6.9 years (1.8-33 years), underwent 64 general anesthetics for diagnostic procedures. Perianesthetic morbidity included need for tracheal reintubation, pneumonitis, hypothermia, and seizure. Therefore, Niemann-Pick disease type C\u2013associated neurologic and visceral involvement might have anesthetic implications that neurologists and pediatricians should be aware of and consider discussing with parents, guardians, and the patient\u2019s care team when procedures requiring anesthesia are planned. Furthermore, it is important for delivery of safe anesthesia that there is communication among care team members so that all involved understand the disease manifestation spectrum.<\/jats:p>","DOI":"10.1177\/0883073812437243","type":"journal-article","created":{"date-parts":[[2012,2,29]],"date-time":"2012-02-29T21:55:54Z","timestamp":1330552554000},"page":"1541-1546","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Niemann-Pick Disease Type C: Implications for Sedation and Anesthesia for Diagnostic Procedures"],"prefix":"10.1177","volume":"27","author":[{"given":"Ning","family":"Miao","sequence":"first","affiliation":[{"name":"Department of Perioperative Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Perioperative Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi P.","family":"O\u2019Grady","sequence":"additional","affiliation":[{"name":"Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Yanjanin","sequence":"additional","affiliation":[{"name":"Section on Molecular Dysmorphology, Program in Developmental Endocrinology and Genetics, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Forbes D.","family":"Porter","sequence":"additional","affiliation":[{"name":"Section on Molecular Dysmorphology, Program in Developmental Endocrinology and Genetics, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenaide M. N.","family":"Quezado","sequence":"additional","affiliation":[{"name":"Department of Perioperative Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA"},{"name":"The Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Medical Center, Washington, DC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,2,28]]},"reference":[{"key":"bibr1-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-006-0384-7"},{"key":"bibr2-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2009.06.008"},{"key":"bibr3-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2009.06.009"},{"key":"bibr4-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-16"},{"key":"bibr5-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2009.12.006"},{"key":"bibr6-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30969"},{"key":"bibr7-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809344222"},{"key":"bibr8-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1097\/01.nrl.0000094627.78754.5b"},{"key":"bibr9-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2003.12.003"},{"key":"bibr10-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63163-X"},{"key":"bibr11-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31735"},{"key":"bibr12-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70194-1"},{"key":"bibr13-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2006.07.016"},{"key":"bibr14-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2002.00922.x"},{"key":"bibr15-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2010.06.018"},{"key":"bibr16-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318208f4ab"},{"key":"bibr17-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1007\/BF02725518"},{"key":"bibr18-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.2000.440609.x"},{"key":"bibr19-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1007\/BF03022961"},{"key":"bibr20-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2004.01538.x"},{"key":"bibr21-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2009.01325.x"},{"key":"bibr22-0883073812437243","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2010.75"},{"issue":"6","key":"bibr23-0883073812437243","first-page":"325","volume":"71","author":"Melloni C","year":"2005","journal-title":"Minerva Anestesiol"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073812437243","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0883073812437243","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073812437243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:37:03Z","timestamp":1777495023000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073812437243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,28]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1177\/0883073812437243"],"URL":"https:\/\/doi.org\/10.1177\/0883073812437243","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,28]]}}}