{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:22:25Z","timestamp":1777803745396,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T00:00:00Z","timestamp":1355270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>Autoimmune myasthenia gravis is rarely seen during infancy. Similar to adults, 85% to 90% of generalized pediatric myasthenia gravis cases have acetylcholine receptor antibodies. Approximately 30% of the remaining cases have antibodies against muscle-specific kinase. Information on the clinical course, treatment alternatives, and prognosis of pediatric muscle-specific kinase antibody\u2013positive myasthenia gravis is limited because of the small number of cases. Here, we present a 14-month-old girl with muscle-specific kinase antibody\u2013positive myasthenia gravis as one of the youngest patients described so far in the literature.<\/jats:p>","DOI":"10.1177\/0883073812467689","type":"journal-article","created":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T21:39:26Z","timestamp":1355348366000},"page":"108-110","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Early-Onset Acquired Myasthenia Gravis Secondary to Anti\u2013Muscle-Specific Kinase Autoantibodies"],"prefix":"10.1177","volume":"29","author":[{"given":"Sanem","family":"Yilmaz","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Child Neurology, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarenur","family":"Gokben","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Child Neurology, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gul","family":"Serdaroglu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Child Neurology, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayfer","family":"Akcay","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Child Neurology, Ege University Faculty of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,12,12]]},"reference":[{"key":"bibr1-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32833c32af"},{"key":"bibr2-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1038\/85520"},{"key":"bibr3-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(03)00306-5"},{"key":"bibr4-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20069"},{"key":"bibr5-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02624.x"},{"key":"bibr6-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21533"},{"key":"bibr7-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1097\/CND.0b013e3181f8a9aa"},{"key":"bibr8-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2008.03.006"},{"key":"bibr9-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000223835.51268.12"},{"key":"bibr10-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5215-2"},{"key":"bibr11-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2008.05.032"},{"key":"bibr12-0883073812467689","doi-asserted-by":"crossref","unstructured":"Saulat B, Maertens P, Hamilton WJ, Bassam BA. Antimusk antibody after thymectomy in a previously seropositive myasthenic child. Neurology. 2007;69:803\u2013804.","DOI":"10.1212\/01.wnl.0000267694.45244.f4"},{"key":"bibr13-0883073812467689","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-3798(11)70335-X"},{"key":"bibr14-0883073812467689","doi-asserted-by":"crossref","unstructured":"Guptill JT, Sanders DB, Evoli A. Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts. 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