{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:57:05Z","timestamp":1787497025459,"version":"build-2736575974"},"reference-count":18,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T00:00:00Z","timestamp":1356652800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>We to report clinical biological and radiologic features of rubella encephalitis in childhood and assess its prognostic impact. Our retrospective study was conducted in an intensive care unit of a university hospital in Sfax, Tunisia. Twenty-one children (age range, 1-15 years) were included. Median age was 9 years (lower and upper quartiles, 7-11 years). On admission, generalized maculopapular eruption was found in 17 cases (81%). Median Glasgow Coma Scale score was 7 (lower and upper quartiles, 7-8). Twenty patients (95.2%) experienced at least 1 episode of seizures. Sixteen patients (76.2%) developed a status epilepticus. The result for enzyme-linked immunosorbent assay detecting anti-rubella immunoglobulin (M) was positive in the serum and in the cerebrospinal fluid samples for all our patients. Magnetic resonance imaging (MRI) of the brain was performed on admission for 3 patients (14.3%) and within a median of 4 days (lower and upper quartiles, 2-6 days) for 8 patients. The test was normal in 6 cases. Two deaths were recorded (9.5%). Survivors had no neurological sequelae 6 months after intensive care unit discharge.<\/jats:p>","DOI":"10.1177\/0883073812469443","type":"journal-article","created":{"date-parts":[[2012,12,28]],"date-time":"2012-12-28T20:46:29Z","timestamp":1356727589000},"page":"49-53","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Childhood Rubella Encephalitis"],"prefix":"10.1177","volume":"29","author":[{"given":"Anis","family":"Chaari","sequence":"first","affiliation":[{"name":"Department of Intensive Care, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mabrouk","family":"Bahloul","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamia","family":"Berrajah","sequence":"additional","affiliation":[{"name":"Department of Virology, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar Ben","family":"Kahla","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nourhene","family":"Gharbi","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hela","family":"Karray","sequence":"additional","affiliation":[{"name":"Department of Virology, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounir","family":"Bouaziz","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Habib Bourguiba University Hospital, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,12,28]]},"reference":[{"key":"bibr1-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2007.12.009"},{"key":"bibr2-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206000636"},{"key":"bibr3-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1177\/08830738060210101701"},{"key":"bibr4-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199311000-00002"},{"key":"bibr5-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-005-0770-7"},{"key":"bibr6-0883073812469443","first-page":"5","author":"Bahloul M","year":"2012","journal-title":"J Infect"},{"key":"bibr7-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15897-2"},{"key":"bibr8-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198811000-00006"},{"key":"bibr9-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-007-6322-6"},{"issue":"15","key":"bibr10-0883073812469443","first-page":"1","volume":"39","author":"Rubella prevention","year":"1990","journal-title":"MMWR Recomm Rep"},{"key":"bibr11-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir479"},{"key":"bibr12-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1590\/S1020-49892011000400005"},{"key":"bibr13-0883073812469443","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.86559"},{"key":"bibr14-0883073812469443","unstructured":"National Register of the Tunisian Public Health Care Ministry, 24 March 2012. www.santetunisie.rns.tn."},{"issue":"447","key":"bibr15-0883073812469443","first-page":"125","volume":"410","author":"Paret G","year":"1993","journal-title":"Harefuah"},{"key":"bibr16-0883073812469443","first-page":"1069","volume-title":"Fiels Virology","volume":"1","author":"Hobman T","year":"2007"},{"key":"bibr17-0883073812469443","doi-asserted-by":"publisher","DOI":"10.1159\/000150543"},{"key":"bibr18-0883073812469443","first-page":"301","volume":"86","year":"2011","journal-title":"Wkly Epidemiol Rec"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073812469443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0883073812469443","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073812469443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:37:43Z","timestamp":1777495063000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073812469443"}},"subtitle":["Diagnosis, Management, and Outcome"],"short-title":[],"issued":{"date-parts":[[2012,12,28]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1177\/0883073812469443"],"URL":"https:\/\/doi.org\/10.1177\/0883073812469443","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,28]]}}}