{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:32:49Z","timestamp":1783776769685,"version":"3.55.0"},"reference-count":41,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2013,5,13]],"date-time":"2013-05-13T00:00:00Z","timestamp":1368403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:p>The main objective was to review the evidence for management of epilepsy associated with hypothalamic hamartomas. We performed a systemic review of the literature through July 2012 that studied patients with hypothalamic hamartomas and related epilepsy. Articles meeting selection criteria were rated according to the American Academy of Neurology classification of evidence scheme. Recommendations were linked to the strength of the evidence and as follows: (a) precocious puberty is associated more with the pedunculated type and epilepsy typified by gelastic seizures with the sessile form of hypothalamic hamartomas (class III); (b) significant behavioral and cognitive deficits are associated with patients with hypothalamic hamartomas (class III); (c) video electroencephalography (EEG) findings are extremely variable particularly across the different ages and do not affect surgical outcome (class III); d) various surgical techniques (transcallosal and endoscopic resection) resulted in 49% to 54% seizure freedom, 15% with a pterional approach as well as about 40% with radiosurgery (class III).<\/jats:p>","DOI":"10.1177\/0883073813488673","type":"journal-article","created":{"date-parts":[[2013,5,13]],"date-time":"2013-05-13T23:28:18Z","timestamp":1368487698000},"page":"909-916","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Diagnosis and Management of Epilepsy Associated With Hypothalamic Hamartoma"],"prefix":"10.1177","volume":"28","author":[{"given":"Sandipan","family":"Pati","sequence":"first","affiliation":[{"name":"Department of Neurology, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Sollman","sequence":"additional","affiliation":[{"name":"Department of Neurology\u2013Neuropsychology, Wake Forest University, Baptist Medical Center, Winston-Salem, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry D.","family":"Fife","sequence":"additional","affiliation":[{"name":"Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Tze","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Child Neurology, College of Medicine, University of Oklahoma, Oklahoma City, OK, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,5,13]]},"reference":[{"key":"bibr1-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2003.10.003"},{"key":"bibr2-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2007.03.003"},{"key":"bibr3-0883073813488673","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.45.221"},{"key":"bibr4-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2005.04.002"},{"key":"bibr5-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1177\/0009922806295400"},{"key":"bibr6-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.4.747"},{"key":"bibr7-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000310644.40767.aa"},{"key":"bibr8-0883073813488673","volume-title":"Clinical Practice Guideline Process Manual","year":"2011"},{"key":"bibr9-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000285084.93652.43"},{"key":"bibr10-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.5.616"},{"key":"bibr11-0883073813488673","first-page":"450","volume":"25","author":"Freeman JL","year":"2004","journal-title":"Am J Neuroradiol"},{"key":"bibr12-0883073813488673","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.2.0212"},{"key":"bibr13-0883073813488673","first-page":"794","volume":"27","author":"Amstutz DR","year":"2006","journal-title":"Am J Neuroradiol"},{"key":"bibr14-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000318279.92233.82"},{"key":"bibr15-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-022018"},{"key":"bibr16-0883073813488673","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1684\/j.1950-6945.2003.tb00017.x","volume":"5","author":"Biesecker LG","year":"2003","journal-title":"Epileptic Disord"},{"key":"bibr17-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.68303.x"},{"key":"bibr18-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2007.10.006"},{"key":"bibr19-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2004.029181"},{"key":"bibr20-0883073813488673","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1684\/j.1950-6945.2003.tb00018.x","volume":"5","author":"Freeman JL","year":"2003","journal-title":"Epileptic Disord"},{"key":"bibr21-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2006.03.016"},{"key":"bibr22-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2008.02.016"},{"key":"bibr23-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00381.x"},{"key":"bibr24-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200106000-00015"},{"key":"bibr25-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1093\/neurosurgery\/47.6.1343"},{"key":"bibr26-0883073813488673","first-page":"33","volume":"91","author":"R\u00e9gis J","year":"2004","journal-title":"Acta Neurochir Suppl"},{"key":"bibr27-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-006-0139-y"},{"key":"bibr28-0883073813488673","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1684\/j.1950-6945.2003.tb00020.x","volume":"5","author":"Harvey AS","year":"2003","journal-title":"Epileptic Disord"},{"key":"bibr29-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2004.03.008"},{"key":"bibr30-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00516.x"},{"key":"bibr31-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.9.1338"},{"key":"bibr32-0883073813488673","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1684\/j.1950-6945.2003.tb00021.x","volume":"5","author":"Fohlen M","year":"2003","journal-title":"Epileptic Disord"},{"issue":"4","key":"bibr33-0883073813488673","first-page":"S336","volume":"59","author":"Procaccini E","year":"2006","journal-title":"Neurosurgery"},{"key":"bibr34-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03095.x"},{"key":"bibr35-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410230502"},{"key":"bibr36-0883073813488673","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1684\/j.1950-6945.2000.tb00347.x","volume":"2","author":"Deonna T","year":"2000","journal-title":"Epileptic Disord"},{"key":"bibr37-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000049457.05670.7D"},{"key":"bibr38-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01455.x"},{"key":"bibr39-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2008.09.008"},{"key":"bibr40-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22298"},{"key":"bibr41-0883073813488673","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2011.02.004"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073813488673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0883073813488673","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073813488673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:38:07Z","timestamp":1777495087000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073813488673"}},"subtitle":["An Evidence-Based Systematic Review"],"short-title":[],"issued":{"date-parts":[[2013,5,13]]},"references-count":41,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1177\/0883073813488673"],"URL":"https:\/\/doi.org\/10.1177\/0883073813488673","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,13]]}}}