{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:47:14Z","timestamp":1792712834727,"version":"4.5.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T00:00:00Z","timestamp":1424995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>\n                    Amplitude-integrated EEG (aEEG) is a commonly used predictor of outcome after hypoxic ischemic encephalopathy. Cerebral and systemic near-infrared spectroscopy and acute kidney injury might also have prognostic value. The authors monitored neonates with aEEG, cerebral and systemic near-infrared spectroscopy during therapeutic hypothermia, assigned an acute kidney injury stage, and measured neurodevelopmental outcome. For 18 infants, cerebral near-infrared spectroscopy variables did not differentiate between those with favorable (n = 13) versus adverse (death or moderate-severe disability; n = 5) 18-month outcomes. However, systemic rSO\n                    <jats:sub>2<\/jats:sub>\n                    variability was higher during hours 48-72 of cooling among those with favorable outcomes (.02 &lt; P &lt; .03). Mean aEEG amplitude during hours 24 to 48 of cooling was higher among those with good outcomes (.027 &lt; P &lt; .032). The aEEG lower margin was also higher during hours 12 to 48 for those with good outcomes (.014 &lt; P &lt; .035). Acute kidney injury did not predict outcome ( P &gt; .05). aEEG is a useful prognostic tool for outcomes after neonatal hypoxic ischemic encephalopathy, but the role of near-infrared spectroscopy in the hypothermia-treated population remains uncertain.\n                  <\/jats:p>","DOI":"10.1177\/0883073815573319","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T21:58:28Z","timestamp":1425074308000},"page":"1526-1531","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["An Evaluation of Cerebral and Systemic Predictors of 18-Month Outcomes for Neonates With Hypoxic Ischemic Encephalopathy"],"prefix":"10.1177","volume":"30","author":[{"given":"Ren\u00e9e A.","family":"Shellhaas","sequence":"first","affiliation":[{"name":"Department of Pediatrics & Communicable Diseases, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juhi S.","family":"Kushwaha","sequence":"additional","affiliation":[{"name":"Wayne State University School of Medicine, Detroit, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa A.","family":"Plegue","sequence":"additional","affiliation":[{"name":"Center for Statistical Consultation and Research, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Selewski","sequence":"additional","affiliation":[{"name":"Department of Pediatrics & Communicable Diseases, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D. E.","family":"Barks","sequence":"additional","affiliation":[{"name":"Department of Pediatrics & Communicable Diseases, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,2,27]]},"reference":[{"key":"bibr1-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0900854"},{"key":"bibr2-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcps050929"},{"key":"bibr3-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17946-X"},{"key":"bibr4-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2011.30"},{"key":"bibr5-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315788"},{"key":"bibr6-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12512"},{"key":"bibr7-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112066"},{"key":"bibr8-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1542\/peds.103.6.1263"},{"key":"bibr9-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1136\/fn.72.1.F34"},{"key":"bibr10-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1136\/fn.81.1.F19"},{"key":"bibr11-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2009.01653.x"},{"key":"bibr12-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2938"},{"key":"bibr13-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2036"},{"key":"bibr14-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-303710"},{"key":"bibr15-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.03.004"},{"key":"bibr16-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0987"},{"key":"bibr17-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.84"},{"key":"bibr18-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-010-9839-x"},{"key":"bibr19-0883073815573319","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.511335"},{"key":"bibr20-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.05.013"},{"key":"bibr21-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31829bfe41"},{"key":"bibr22-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.230"},{"key":"bibr23-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.10.002"},{"key":"bibr24-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32834f62d5"},{"key":"bibr25-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2014.10"},{"key":"bibr26-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1997.tb07414.x"},{"key":"bibr27-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2011.09.008"},{"key":"bibr28-0883073815573319","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.133"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073815573319","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0883073815573319","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073815573319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:37:53Z","timestamp":1777495073000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073815573319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,27]]},"references-count":28,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1177\/0883073815573319"],"URL":"https:\/\/doi.org\/10.1177\/0883073815573319","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,27]]}}}