{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:24:42Z","timestamp":1792481082601,"version":"4.5.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T00:00:00Z","timestamp":1434326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p>Using resting state functional magnetic resonance imaging (MRI), we aim to understand the neurologic basis of improved function in children with hemiplegic cerebral palsy treated with constraint-induced movement therapy. Eleven children including 4 untreated comparison subjects diagnosed with hemiplegic cerebral palsy were recruited from 3 clinical centers. MRI and clinical data were gathered at baseline and 1 month for both groups, and 6 months later for the case group only. After constraint therapy, the sensorimotor resting state network became more bilateral, with balanced contributions from each hemisphere, which was sustained 6 months later. Sensorimotor resting state network reorganization after therapy was correlated with a change in the Quality of Upper Extremity Skills Test score at 1 month (r = 0.79, P = .06), and Canadian Occupational Performance Measure scores at 6 months (r = 0.82, P = .05). This clinically correlated resting state network reorganization provides further evidence of the neuroplastic mechanisms underlying constraint-induced movement therapy.<\/jats:p>","DOI":"10.1177\/0883073815588995","type":"journal-article","created":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T21:20:20Z","timestamp":1434403220000},"page":"220-226","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":33,"title":["Neuroplastic Sensorimotor Resting State Network Reorganization in Children With Hemiplegic Cerebral Palsy Treated With Constraint-Induced Movement Therapy"],"prefix":"10.1177","volume":"31","author":[{"given":"Kathryn Y.","family":"Manning","sequence":"first","affiliation":[{"name":"Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi S.","family":"Menon","sequence":"additional","affiliation":[{"name":"Robarts Research Institute, University of Western Ontario, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Willem","family":"Gorter","sequence":"additional","affiliation":[{"name":"CanChild Centre for Childhood Disability Research, McMaster University and McMaster Children\u2019s Hospital, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronit","family":"Mesterman","sequence":"additional","affiliation":[{"name":"CanChild Centre for Childhood Disability Research, McMaster University and McMaster Children\u2019s Hospital, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Switzer","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University of Toronto, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darcy","family":"Fehlings","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University of Toronto, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,6,15]]},"reference":[{"key":"bibr1-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12246"},{"key":"bibr2-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1310\/BLJX-M89N-PTPY-JDKW"},{"key":"bibr3-0883073815588995","first-page":"8","volume":"109","author":"Rosenbaum P","year":"2007","journal-title":"Dev Med Child Neurol"},{"key":"bibr4-0883073815588995","first-page":"371","volume-title":"Behavioral Psychology in Rehabilitation Medicine: Clinical Applications","author":"Taub E","year":"1980"},{"issue":"2","key":"bibr5-0883073815588995","first-page":"CD004149","author":"Hoare BJ","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr6-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1177\/0883073815572686"},{"key":"bibr7-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1097\/00146965-200603000-00005"},{"key":"bibr8-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03119.x"},{"key":"bibr9-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70525-7"},{"key":"bibr10-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf227"},{"key":"bibr11-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(98)00386-3"},{"key":"bibr12-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1177\/0883073807307084"},{"key":"bibr13-0883073815588995","first-page":"269","volume":"42","author":"Mark VW","year":"2006","journal-title":"Eura Medicophys"},{"key":"bibr14-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-985904"},{"key":"bibr15-0883073815588995","doi-asserted-by":"publisher","DOI":"10.3109\/17518420903236247"},{"key":"bibr16-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.02.070"},{"key":"bibr17-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1177\/1545968312457827"},{"key":"bibr18-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1310\/tsr1604-270"},{"key":"bibr19-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.596155"},{"key":"bibr20-0883073815588995","volume-title":"International Classification of Functioning, Disability and Health","author":"World Health Organization","year":"2007"},{"key":"bibr21-0883073815588995","doi-asserted-by":"publisher","DOI":"10.3109\/01942638.2011.602389"},{"key":"bibr22-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.12.063"},{"key":"bibr23-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0905267106"},{"key":"bibr24-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh600"},{"key":"bibr25-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2009.03306.x"},{"key":"bibr26-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.10.059"},{"key":"bibr27-0883073815588995","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.02.025"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073815588995","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0883073815588995","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0883073815588995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:38:04Z","timestamp":1777495084000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0883073815588995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,15]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1177\/0883073815588995"],"URL":"https:\/\/doi.org\/10.1177\/0883073815588995","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,15]]}}}