{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:17:25Z","timestamp":1793121445593,"version":"4.5.0"},"reference-count":45,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T00:00:00Z","timestamp":1539216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The present study aimed to investigate whether the response variability of infants to modified constraint-induced movement therapy and bimanual therapy are associated with different types of brain lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>Infants with unilateral cerebral palsy (N = 22) ages 8-15 months (mean = 10.95, standard deviation = 2.15 months) were grouped according to having either a periventricular brain lesion or a middle cerebral artery infarct lesion. Improvement in hand function was analyzed based on the mini\u2013Assistive Hand Assessment results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Infants with periventricular brain lesion displayed greater positive response to upper limb treatment compared to those with middle cerebral artery infarct (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .02). A significant difference in improvement according to type of treatment was found in the middle cerebral artery infarct group but not in the periventricular brain lesion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The present study showed an association between the type of brain lesion and the efficacy of upper limb treatment in infants. Infants with periventricular brain lesions displayed greater positive responses than those with middle cerebral artery infarct.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0883073818801632","type":"journal-article","created":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T09:19:17Z","timestamp":1539249557000},"page":"918-924","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Brain Lesions as a Predictor of Therapeutic Outcomes of Hand Function in Infants With Unilateral Cerebral Palsy"],"prefix":"10.1177","volume":"33","author":[{"given":"Rena","family":"Chamudot","sequence":"first","affiliation":[{"name":"School of Occupational Therapy, Faculty of Medicine, Hebrew University of Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shula","family":"Parush","sequence":"additional","affiliation":[{"name":"School of Occupational Therapy, Faculty of Medicine, Hebrew University of Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amihai","family":"Rigbi","sequence":"additional","affiliation":[{"name":"Research Authority and Faculty of Education, Beit Berl Academic College, Kfar-Sava, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varda","family":"Gross-Tsur","sequence":"additional","affiliation":[{"name":"Neuropediatric Unit, Shaare Zedek Medical Center"},{"name":"The Hebrew University School of Medicine, Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,10,11]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2007.tb12610.x"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000117981.35364.1B"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2009.03.009"},{"issue":"12","key":"e_1_3_3_5_2","first-page":"828","article-title":"Impact of impairment on activity patterns of children","volume":"68","author":"Brown M","year":"1987","unstructured":"Brown M, Gordon WA. 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