{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T01:32:46Z","timestamp":1790040766716,"version":"4.0.1"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T00:00:00Z","timestamp":1542067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Importance:<\/jats:title>\n                    <jats:p>Congenital Zika syndrome virus infection is said to interfere in children\u2019s development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>evaluate gross motor trajectories and the frequency of cerebral palsy in children with congenital Zika syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Cohort study applying the Alberta Infant Motor Scale (AIMS) and the Bayley III Scales in infants from 6 to 18 months of age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>The SARAH network, Rio de Janeiro.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants:<\/jats:title>\n                    <jats:p>Thirty-nine infants whose diagnoses were established through clinical history, serology tests, and neuroimaging findings. Main outcomes and measures: Congenital Zika syndrome is associated with severe motor delays and is a risk factor to the diagnosis of cerebral palsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The Alberta Infant Motor Scale mean raw score at 6 months was 9.74 (SD 4.80) or equivalent to 2 to 3 months of motor developmental age. At the age of 12 months, 14.13 (SD 11.90), corresponding to 3 to 4 months of motor development age; the Bayley III Scales results correlated to the Alberta Infant Motor Scale ( P &lt; .001) at this age. At 18 months, 15.77 (SD 13.80) or a motor development equivalent to 4 to 5 months of age. Thirty-five of 39 children (89.7%) met criteria for the diagnosis of cerebral palsy. Conclusions and relevance: Gross motor development marginally progresses from 6 to 18 months of age. These individuals also displayed a high frequency of cerebral palsy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0883073818811234","type":"journal-article","created":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T07:34:40Z","timestamp":1542094480000},"page":"81-85","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":47,"title":["Children Born With Congenital Zika Syndrome Display Atypical Gross Motor Development and a Higher Risk for Cerebral Palsy"],"prefix":"10.1177","volume":"34","author":[{"given":"Fernanda J. P.","family":"Marques","sequence":"first","affiliation":[{"name":"SARAH Network of Rehabilitation Hospitals, Rio de Janeiro, Brazil"},{"name":"Federal Fluminense University, Niter\u00f3i, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta C. S.","family":"Teixeira","sequence":"additional","affiliation":[{"name":"SARAH Network of Rehabilitation Hospitals, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael R.","family":"Barra","sequence":"additional","affiliation":[{"name":"SARAH Network of Rehabilitation Hospitals, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda M.","family":"de Lima","sequence":"additional","affiliation":[{"name":"SARAH Network of Rehabilitation Hospitals, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno L. Scofano","family":"Dias","sequence":"additional","affiliation":[{"name":"SARAH Network of Rehabilitation Hospitals, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Pupe","sequence":"additional","affiliation":[{"name":"Federal Fluminense University, Niter\u00f3i, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osvaldo J. M.","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Federal Fluminense University, Niter\u00f3i, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2929-8416","authenticated-orcid":false,"given":"Marcio","family":"Leyser","sequence":"additional","affiliation":[{"name":"University of Iowa Stead Family Department of Pediatrics, Iowa City, IA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,11,13]]},"reference":[{"key":"bibr1-0883073818811234","unstructured":"Early Childhood Development: The key to a full and productive life. 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