{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:31:40Z","timestamp":1777804300662,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T00:00:00Z","timestamp":1593388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To develop an orthostatic intolerance symptom scoring system to assess orthostatic intolerance and then to compare the symptom score among different head-up tilt test responses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>272 subjects (5-18 years) presenting with orthostatic intolerance symptoms finished questionnaire and head-up tilt test. According to head-up tilt test hemodynamic responses, the subjects were divided into head-up tilt test negative, vasovagal syncope, and postural tachycardia syndrome groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We built up a symptom score according to the frequency of dizziness, headache, blurred vision, palpitations, chest discomfort, gastrointestinal symptoms, profuse perspiration, and syncope. The median score in postural tachycardia syndrome subjects was highest. A score of 2.5 for predicting vasovagal syncope yielded a sensitivity of 75.0% and specificity of 50.3%, a score of 5.5 for predicting postural tachycardia syndrome yielded a sensitivity of 69.7% and specificity of 72.0%. Furthermore, the median score in postural tachycardia syndrome subjects was significantly higher than that in head-up tilt test negative subjects with heart rate increment of 30-39 beats\/min ( P &lt; .01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This suggests that the symptom score has some predictive value in head-up tilt test results, which can be served as a preliminary assessment instrument.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0883073820936025","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T02:11:05Z","timestamp":1593483065000},"page":"835-843","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Symptom Score: A New Instrument to Assess Orthostatic Intolerance in Children and Adolescents"],"prefix":"10.1177","volume":"35","author":[{"given":"Hong","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiovasology, Children\u2019s Medical Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovasology, Children\u2019s Medical Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China."},{"name":"Jishou University School of Medicine, Jishou, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runmei","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovasology, Children\u2019s Medical Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovasology, Children\u2019s Medical Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovasology, Children\u2019s Medical Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuwen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiovasology, Children\u2019s Medical Center, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 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