{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:32:13Z","timestamp":1777804333182,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>The epidemiology of demyelinating diseases in the Korean pediatric population has not been reported to date. This study aimed to identify the epidemiology of demyelinating diseases in Korean children by using big data. The subjects were children (0-17 years old) diagnosed with acute-disseminated encephalomyelitis, multiple sclerosis, neuromyelitis optica, and Guillain-Barr\u00e9 syndrome enrolled in the Korean Health Insurance Review and Assessment Service (HIRA) from January 2010 to December 2017.<\/jats:p>\n                  <jats:p>Of 1722 enrolled children, 553 (32.1%) had acute-disseminated encephalomyelitis, 170 (9.9%) had multiple sclerosis, 68 (3.9%) had neuromyelitis optica, and 931 (54.1%) had Guillain-Barr\u00e9 syndrome. The male-female ratios were 1.47:1 in acute-disseminated encephalomyelitis, 1.43:1 in Guillain-Barr\u00e9 syndrome, 1:1.66 in multiple sclerosis, and 1:1.62 in neuromyelitis optica. Demyelinating diseases were most prevalent in summer. The prevalence differed by region, with 545 (31.6%) in Seoul and 298 (17.3%) in Gyeonggi. This study is the first to identify the incidence of demyelinating diseases in South Korea.<\/jats:p>","DOI":"10.1177\/0883073820959543","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T22:40:07Z","timestamp":1601332807000},"page":"141-147","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Epidemiology of Demyelinating Diseases in Korean Pediatric Patients"],"prefix":"10.1177","volume":"36","author":[{"given":"Hye Hyun","family":"Yoon","sequence":"first","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Young","family":"Park","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su Yeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na Mi","family":"Lee","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Yong","family":"Yi","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sin Weon","family":"Yun","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In Seok","family":"Lim","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9825-8194","authenticated-orcid":false,"given":"Soo Ahn","family":"Chae","sequence":"additional","affiliation":[{"name":"Chung-Ang University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,9,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000928"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0883073819845827"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2012-048"},{"issue":"4","key":"e_1_3_3_5_2","first-page":"65","article-title":"Epidemiological, clinical, and laboratory characteristics of acute disseminated encephalomyelitis in children: a retrospective study","volume":"13","author":"Taghdiri MM","year":"2019","unstructured":"Taghdiri MM, Amouzadeh MH, Esmail Nejad SS, Abasi E, Alipour A, Akhavan M. 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