{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:27:46Z","timestamp":1790310466951,"version":"4.1.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>Dandy-Walker continuum, which includes Dandy-Walker malformation, vermian hypoplasia, and Blake pouch cyst, is among the most commonly diagnosed posterior fossa malformation by fetal magnetic resonance imaging (MRI). The objective of our retrospective study was to evaluate fetal and postnatal MRI scan and clinical outcomes. Seventy-two patients were identified; 40 patients had postnatal imaging and follow-up (7 Dandy-Walker malformation, 26 vermian hypoplasia, and 7 Blake pouch cyst). Although all patients with Dandy-Walker malformation required ventriculoperitoneal shunts and 66% were intubated at birth, none required tracheostomy tube and 2 of 5 surviving children had no neurologic deficits. Vermian hypoplasia was strongly associated with genetic conditions and cardiac malformations; odds of not ambulating normally were 12 times greater if a syndrome or injury was present. Echocardiogram and genetic screening are recommended with vermian hypoplasia. There is a risk for epilepsy in both Dandy-Walker malformation and vermian hypoplasia. Blake pouch cyst can be complicated by hydrocephalus, but outcome is favorable.<\/jats:p>","DOI":"10.1177\/08830738211049115","type":"journal-article","created":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T12:59:06Z","timestamp":1636549146000},"page":"1111-1119","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Short- and Long-Term Outcomes of Prenatally Diagnosed Dandy-Walker Malformation, Vermian Hypoplasia, and Blake Pouch Cyst"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8763-4836","authenticated-orcid":false,"given":"Charu","family":"Venkatesan","sequence":"first","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Kline- Fath","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"},{"name":"Division of Radiology and Medical Imaging, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Horn","sequence":"additional","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey E.","family":"Poisson","sequence":"additional","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Hopkin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"},{"name":"Division of Human Genetics, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usha D.","family":"Nagaraj","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"},{"name":"Division of Radiology and Medical Imaging, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,11,10]]},"reference":[{"key":"bibr1-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1159\/000380821"},{"key":"bibr2-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13429"},{"key":"bibr3-08830738211049115","doi-asserted-by":"publisher","DOI":"10.3233\/NPM-14814005"},{"issue":"5","key":"bibr4-08830738211049115","first-page":"977","volume":"10","author":"Barkovich AJ","year":"1989","journal-title":"Am J Roentgenol"},{"key":"bibr5-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1007\/BF00301017"},{"key":"bibr6-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03224.x"},{"key":"bibr7-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11071"},{"key":"bibr8-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-010-1085-2"},{"key":"bibr9-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2911"},{"key":"bibr10-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-304054"},{"key":"bibr11-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.13.6.8031352"},{"key":"bibr12-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2016.04.007"},{"key":"bibr13-08830738211049115","doi-asserted-by":"crossref","unstructured":"Nagaraj UD, Kline-Fath B, Horn P, Venkatesan C. Evaluation of posterior fossa biometric measurements on fetal MRI in the evaluation of Dandy-Walker continuum.\n                      AJNR Am J Neuroradiol.\n                      2021;42(9):1716-1721.","DOI":"10.3174\/ajnr.A7215"},{"key":"bibr14-08830738211049115","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2020.09.039"}],"container-title":["Journal of Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08830738211049115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/08830738211049115","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/08830738211049115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:40:16Z","timestamp":1777495216000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/08830738211049115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1177\/08830738211049115"],"URL":"https:\/\/doi.org\/10.1177\/08830738211049115","relation":{},"ISSN":["0883-0738","1708-8283"],"issn-type":[{"value":"0883-0738","type":"print"},{"value":"1708-8283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}