{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:22:40Z","timestamp":1787012560681,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Takayasu arteritis is a rare granulomatous chronic vasculitis that affects the aorta and its main branches. Neurologic manifestations can accompany the disease; however, there is no study on neuroimaging in children with Takayasu arteritis. Therefore, we aimed to evaluate cranial magnetic resonance imaging (MRI) in pediatric Takayasu arteritis patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Demographic, clinical, and laboratory data were obtained retrospectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The study included 15 pediatric Takayasu arteritis patients. All patients presented with constitutional symptoms. Additionally, 6 patients suffered from headache, 2 had syncope, 1 had loss of consciousness, and 1 had convulsion. All patients underwent cranial and diffusion MRI a median 12 months after diagnosis. Cranial MRI findings were normal in 12 patients, whereas 3 patients had abnormal findings, as follows: stenosis in the M1 and M2 segments of the left middle cerebral artery (n = 1); diffuse thinning of the right internal carotid, middle cerebral, and right vertebral and basilar artery (n = 1); as a sequela, areas of focal gliosis in both the lateral ventricular and posterior periventricular regions (n = 1). Among these 3 patients, 1 had no neurologic complaints.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Abnormal MRI findings can be observed in pediatric Takayasu arteritis patients, even those that are asymptomatic; therefore, clinicians should carefully evaluate neurologic involvement in all pediatric Takayasu arteritis patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0883073821991287","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T20:21:41Z","timestamp":1613852501000},"page":"642-647","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Neuroimaging of Children With Takayasu Arteritis"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9186-3068","authenticated-orcid":false,"given":"Hafize Emine","family":"S\u00f6nmez","sequence":"first","affiliation":[{"name":"Division of Pediatrics, Department of Pediatric Rheumatology, Kocaeli University, Kocaeli, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferhat","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, \u00dcmraniye Research and Training Hospital, University of Health Science, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semanur","family":"\u00d6zdel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Sami Ulus Research and Training Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eerife G\u00fcl","family":"Karada\u011f","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Sadi Konuk Research and Training Hospital, University of Health Science, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Ba\u011flan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Sami Ulus Research and Training Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"B\u00fclb\u00fcl","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Sami Ulus Research and Training Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"\u00c7akan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Zeynep Kamil Research and Training Hospital, University of Health Sciences, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuray Aktay","family":"Ayaz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Istanbul University Medical School, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"S\u00f6zeri","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, \u00dcmraniye Research and Training Hospital, University of Health Science, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"bibr1-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.116657"},{"key":"bibr2-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-010-1496-1"},{"key":"bibr3-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012547"},{"key":"bibr4-0883073821991287","first-page":"196","volume":"26","author":"Ozen S","year":"2007","journal-title":"Clin Rheumatol"},{"key":"bibr5-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12718"},{"key":"bibr6-0883073821991287","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-120-11-199406010-00004"},{"issue":"1","key":"bibr7-0883073821991287","first-page":"11","volume":"93","author":"Churg J","year":"1993","journal-title":"Clin Exp Immunol"},{"key":"bibr8-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2004.04.026"},{"key":"bibr9-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0545-1"},{"key":"bibr10-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-018-1790-x"},{"key":"bibr11-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/key322"},{"key":"bibr12-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(96)02813-6"},{"key":"bibr13-0883073821991287","doi-asserted-by":"publisher","DOI":"10.1177\/000331979704800501"},{"key":"bibr14-0883073821991287","first-page":"1795","volume":"52","author":"Misra R","year":"2013","journal-title":"Development and initial validation of the Indian Takayasu Clinical Activity Score (ITAS2010). 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