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A cross-sectional retrospective chart review was completed on a large cohort of children with Down syndrome from birth to 6 years of age who completed the Peabody Developmental Motor Scales\u20132nd Edition (PDMS-2). Although both fine motor and visual motor development were delayed in children with Down syndrome compared with typically developing peers, and a negative association between fine motor quotient and age was observed, grasping and visual motor integration raw scores increased with age. The Down syndrome\u2013specific percentile curves developed here may enable providers to identify individuals requiring further investigation, and will be useful in future studies of factors that may influence fine motor development in Down syndrome. These data will also help parents better understand their children's development and interpret developmental test results.<\/jats:p>","DOI":"10.1177\/08830738251387929","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T16:50:49Z","timestamp":1765558249000},"page":"1107-1118","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Fine Motor Development Growth Curves for Down Syndrome"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0382-4481","authenticated-orcid":false,"given":"Mandie","family":"Wiebers Jensen","sequence":"first","affiliation":[{"name":"Neurodevelopmental Pediatrics \/ Institute on Development and Disability, Oregon Health &amp; Science University, Portland, OR, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Wolf","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Feryn","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuan","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Oregon Health & Science University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Katlaps","sequence":"additional","affiliation":[{"name":"University of California San Diego"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph D.","family":"Pinter","sequence":"additional","affiliation":[{"name":"Providence St Vincent Medical Center, Pediatric Neurology"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20735"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-010418-102836"},{"key":"e_1_3_2_4_2","first-page":"548","article-title":"Performance of Down syndrome individuals on the Stanford-Binet Intelligence Scale","volume":"86","author":"Silverstein AB","year":"1982","unstructured":"Silverstein AB, Legutki G, Friedman SL, Takayama DL. 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