{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:38:32Z","timestamp":1787063912573,"version":"build-2736575974"},"reference-count":26,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Beijing Municipal Natural Science Foundation","award":["M22013"],"award-info":[{"award-number":["M22013"]}]},{"name":"the CAMS Innovation Fund for Medical Sciences","award":["CIFMS 2021-I2M-1-003"],"award-info":[{"award-number":["CIFMS 2021-I2M-1-003"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82103302 to MC"],"award-info":[{"award-number":["82103302 to MC"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the National High Level Hospital Clinical Research Funding","award":["2022-PUMCH-C-012"],"award-info":[{"award-number":["2022-PUMCH-C-012"]}]},{"name":"the Key Area Research and Development Program of Guangdong Province","award":["2021B0101420005"],"award-info":[{"award-number":["2021B0101420005"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Meningitis remains a major cause of morbidity and mortality among children aged 0-14 years, especially in low- and middle-income countries, despite global advances in vaccines and health care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Based on Global Burden of Disease (GBD) 2021 data, we assessed meningitis-related prevalence, mortality, and disability-adjusted life years (DALYs) in children aged 0-14 across 204 countries from 1990 to 2021, stratified by age, sex, region, and Socio-demographic Index (SDI). Trends were evaluated using Estimated Annual Percentage Change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 1990 to 2021, global prevalence, deaths, and DALYs declined by 52.0%, 69.2%, and 69.1%, respectively. The highest burden in 2021 was observed in Sub-Saharan Africa and South Asia. Disease burden showed wide geographic variation and was inversely correlated with SDI. Leading attributable risks included malnutrition and behavioral factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although meningitis burden has decreased globally, regional disparities persist. Sustained vaccination, health system strengthening, and targeted interventions in high-burden areas remain critical to reducing preventable childhood deaths and disabilities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08830738251399249","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T12:42:55Z","timestamp":1764765775000},"page":"949-960","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Global, Regional, and National Burden of Meningitis in Children Aged 0-14 Years From 1990 to 2021: Trends and Disparities Based on the Global Burden of Disease Study"],"prefix":"10.1177","volume":"41","author":[{"given":"Shuangjian","family":"Yang","sequence":"first","affiliation":[{"name":"Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical 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