{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T10:46:00Z","timestamp":1777805160245,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Neurol"],"abstract":"<jats:p>This study evaluates the clinical profiles and treatment outcomes of 5 children with chronic inflammatory demyelinating polyneuropathy at a pediatric neurology clinic in northern India over 3 years. The patients, aged 2.5-13 years, included 4 with motor sensory polyneuropathy and 1 with pure motor polyneuropathy. The most affected age group was late childhood to early adolescence, with a male-to-female ratio of 3:2. All patients responded well to intravenous pulse therapy with methylprednisolone; 60% had a good response, and 40% showed partial improvement. One child with pure motor neuropathy required additional intravenous immunoglobulin and rituximab. Ultimately, 60% of the children achieved a life without disability, and 40% reached stable, nonprogressive conditions following treatment. This highlights corticosteroids\u2019 critical role as a first-line treatment in low-resource settings and the importance of accurate nerve conduction studies.<\/jats:p>","DOI":"10.1177\/08830738261433227","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T10:38:43Z","timestamp":1775212723000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["From Diagnosis to Recovery: Charting the Path of Children With Chronic Inflammatory Demyelinating Polyneuropathy in a Tertiary Care Setting"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8057-9128","authenticated-orcid":false,"given":"Varsha","family":"Mishra","sequence":"first","affiliation":[{"name":"All India Institute of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachna","family":"Sehgal","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Archana","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meenakshi","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamsuddin","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.128132"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2019.04.021"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000481"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23629"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2010.00290.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2018.06.001"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-017-2536-5"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2012.09.008"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.667378"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51432"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21480"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(00)00119-X"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2018.06.001"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.667378"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2015.04.001"},{"key":"e_1_3_3_17_2","first-page":"210","article-title":"Chronic inflammatory demyelinating polyradiculopathy: an atypical pediatric case complicated with phrenic nerve palsy","volume":"49","author":"Polat M","year":"2007","unstructured":"Polat M, Tosun A, Serdaro\u011flu G, et al. Chronic inflammatory demyelinating polyradiculopathy: an atypical pediatric case complicated with phrenic nerve palsy. Turk J Pediatr. 2007;49:210-214.","journal-title":"Turk J Pediatr"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2011.12.003"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2012.09.008"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21058"},{"key":"e_1_3_3_21_2","doi-asserted-by":"crossref","unstructured":"Hughes RA Mehndiratta MM Rajabally YA. Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy \u2013 Hughes RAC \u2013 2017 \/ Cochrane Library. 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