{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T09:46:45Z","timestamp":1777801605998,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[1995,3]]},"abstract":"<jats:p>Based on the initial successful use of felbamate for infantile spasms in an infant with tuberous sclerosis, three additional infants with infantile spasms of different etiologies who had failed conventional therapies were treated with felbamate. Three of the four patients have shown complete resolution of infantile spasms. All responding patients did so within 1 week of starting felbamate. The one treatment failure had an initial reduction of seizure frequency and severity but has not maintained that response long term. Controlled studies are needed to firmly establish that felbamate is both safe and effective for the treatment of infantile spasms. As these cases document, felbamate is currently available for use in infantile spasms, and the frequent conversion of infantile spasms to Lennox-Gastaut syndrome, for which felbamate is approved, makes its use in infantile spasms logical. (J Child Neurol 1995;10:134-136).<\/jats:p>","DOI":"10.1177\/088307389501000215","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T02:13:25Z","timestamp":1230084805000},"page":"134-136","source":"Crossref","is-referenced-by-count":39,"title":["The Use of Felbamate to Treat Infantile Spasms"],"prefix":"10.1177","volume":"10","author":[{"given":"Daniel L.","family":"Hurst","sequence":"first","affiliation":[{"name":"Department of Neurology, Texas Tech University School of Medicine, Lubbock, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry D.","family":"Rolan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Texas Tech University School of Medicine, Lubbock, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1995,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.4.693"},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/0140-6736(93)90888-N","volume":"341","author":"Brodie MJ","year":"1993","journal-title":"Lancet"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.4.688"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301073280105"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320313"},{"key":"atypb6","unstructured":"Jeavons PM , Livet MO: West syndrome: Infantile spasms, in Roger J, Bureau M, Dravet C (eds): Epileptic Syndromes in Infancy, Childhood and Adolescence, 2nd ed. London , John Libbey, 1992, pp 53-63."},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270408"},{"key":"atypb8","unstructured":"Holmes GL: Infantile spasms, in Markowitz M (ed): Diagnosis and Management of Seizures in Children. Philadelphia, WB Saunders, 1987, pp 212-225."},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30339-6"},{"key":"atypb10","unstructured":"Hrachovy RA , Frost JD: Severe encephalopathic epilepsy in infants: Infantile spasms, in Dodson WE, Pellock JM (eds): Pediatric Epilepsy: Diagnosis and Therapy . New York, Demos Publications , 1993 , pp 135-145."},{"key":"atypb11","doi-asserted-by":"crossref","unstructured":"Fenichel GM : Paroxysmal disorders of newborns, in Fenichel GM (ed): Clinical Pediatric Neurology, a Signs and Symptoms Approach. Philadelphia , WB Saunders , 1993, pp 1-43.","DOI":"10.1016\/B978-1-4160-6185-4.00001-0"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1988.tb03761.x"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(87)80115-8"},{"key":"atypb14","unstructured":"Perhach JL , Weliky I., Newton JJ, et al: Felbamate, in Meldrum BS, Porter RJ (eds): New Anticonvulsant Drugs . London, John Libbey, 1986, pp 117-123."},{"issue":"3","key":"atypb15","first-page":"118","volume":"33","author":"Sachdeo RC","year":"1992","journal-title":"Epilepsia"},{"key":"atypb16","unstructured":"Weinmann HM : Lennox-Gastaut syndrome and its relationship to infantile spasms (West syndrome) , in Niedermeyer E, Degen R (eds): The Lennox-Gastaut Syndrome . New York, Alan R. Liss, 1988, pp 301-316."},{"key":"atypb17","unstructured":"Aicardi J. : Infantile spasms and related syndromes, in Epilepsy in Children, The International Review of Child Neurology , 2nd ed, vol 3. New York, Raven Press, 1994, pp 18-43."},{"key":"atypb18","unstructured":"Larson HJ: Introduction to Probability Theory and Statistical Inference, vol 4. 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