{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:02:34Z","timestamp":1790143354318,"version":"4.0.1"},"reference-count":28,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Child Neurol"],"published-print":{"date-parts":[[1998,7]]},"abstract":"<jats:p>There is strong evidence for a loss of habituation during cognitive processing in migraine as measured by P300 and contingent negative variation in adults. Event-related potentials evoked by an oddball paradigm have not yet been studied in children and adolescents suffering from different primary headache types. We recorded visually evoked event-related potentials (two consecutive trials, 200 stimuli each) in 48 children and adolescents suffering from migraine without or with aura, from episodic tension-type headache, and from ergotamine-induced headache and analyzed the latencies, amplitudes, and reaction times. No statistically significant differences were noted between all headache types and healthy controls analyzing the averaged parameters for the whole measurement. However, a highly significant loss of cortical habituation as measured by P300 amplitude and latency could be observed in migraine without and with aura by analyzing the first and the second trial of measurement separately. This phenomenon increased with age and could not be seen in healthy controls, or patients with tension-type headache or ergotamine-induced headache. Our data suggest a specific cognitive processing in migraine even in children and adolescents. Measurement of the habituation effect in P300 latency and amplitude provides a specific method to differentiate between primary headache types in childhood and adolescence. (J Child Neurol 1998;13:322-326).<\/jats:p>","DOI":"10.1177\/088307389801300703","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T02:13:25Z","timestamp":1230084805000},"page":"322-326","source":"Crossref","is-referenced-by-count":41,"title":["Event-Related Potentials (P300) in Primary Headache in Childhood and Adolescence"],"prefix":"10.1177","volume":"13","author":[{"given":"Stefan","family":"Evers","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Munster, Munster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Munster, Munster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-H.","family":"Grotemeyer","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Munster, Munster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Kurlemann","sequence":"additional","affiliation":[{"name":"Department of Neuropediatrics University of Munster, M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo-W.","family":"Husstedt","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Munster, Munster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1998,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1993.1301037.x"},{"key":"atypb2","first-page":"181","volume":"7","author":"Schoenen J.","year":"1992","journal-title":"Funct Neurol"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1989.hed22904239.x"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1177\/0333102491011S1139"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1177\/0333102489009S1063"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.1.108"},{"issue":"14","key":"atypb7","first-page":"64","volume":"15","author":"Wang W.","year":"1995","journal-title":"Cephalalgia"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1990.hed3009604.x"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410190115"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1993.1301042.x"},{"issue":"13","key":"atypb11","first-page":"214","volume":"13","author":"Pothmann R.","year":"1993","journal-title":"Cephalalgia"},{"key":"atypb12","unstructured":"Berg BO: Headache, in Berg BO (ed): Child Neurology. 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